User profiles for Robert B. Innis
Robert B InnisSenior Investigator Verified email at nih.gov Cited by 49842 |
Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands
RB Innis, VJ Cunningham, J Delforge… - Journal of Cerebral …, 2007 - journals.sagepub.com
… With this nomenclature, BP without subscript refers to the ‘true’ in vitro measurement of B
max /K D , and BP with subscripts refers to in vivo measurements that reflect, but typically do …
max /K D , and BP with subscripts refers to in vivo measurements that reflect, but typically do …
[HTML][HTML] MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder
Objective Studies in nonhuman primates suggest that high levels of cortisol associated with
stress have neurotoxic effects on the hippocampus, a brain structure involved in memory. …
stress have neurotoxic effects on the hippocampus, a brain structure involved in memory. …
Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a …
…, C Mazure, S Capelli, G McCarthy, RB Innis… - Biological …, 1997 - Elsevier
We have previously reported smaller hippocampal volume and deficits in short-term memory
in patients with combat-related posttraumatic stress disorder (PTSD) relative to comparison …
in patients with combat-related posttraumatic stress disorder (PTSD) relative to comparison …
Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort
…, CH van Dyck, DS Charney, RB Innis… - American journal of …, 1998 - Am Psychiatric Assoc
OBJECTIVE: The authors previously observed an increase in striatal dopamine transmission
following amphetamine challenge in 15 untreated patients with schizophrenia compared to …
following amphetamine challenge in 15 untreated patients with schizophrenia compared to …
[HTML][HTML] Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl) tropane and single photon …
Background: Prior research has suggested reductions in the density of serotonin transporter
(SERT) binding sites in blood platelets and post-mortem brain tissue of depressed patients. …
(SERT) binding sites in blood platelets and post-mortem brain tissue of depressed patients. …
Deficits in short-term memory in posttraumatic stress disorder.
…, JW Mason, DR Johnson, RB Innis… - The American journal …, 1993 - europepmc.org
Objective The purpose of this study was to compare the memory function of patients with
posttraumatic stress disorder (PTSD) to that of matched comparison subjects. Method Vietnam …
posttraumatic stress disorder (PTSD) to that of matched comparison subjects. Method Vietnam …
Linearized Reference Tissue Parametric Imaging Methods: Application to [11C]DASB Positron Emission Tomography Studies of the Serotonin Transporter in Human …
…, T Suhara, K Suzuki, RB Innis… - Journal of Cerebral …, 2003 - journals.sagepub.com
The authors developed and applied two new linearized reference tissue models for parametric
images of binding potential (BP) and relative delivery (R 1 ) for [ 11 C]DASB positron …
images of binding potential (BP) and relative delivery (R 1 ) for [ 11 C]DASB positron …
Distinct cholecystokinin receptors in brain and pancreas.
RB Innis, SH Snyder - … of the National Academy of Sciences, 1980 - National Acad Sciences
125I-Labeled (Bolton-Hunter) cholecystokinin triacontatriapeptide (CCK-33) binds saturably
and reversibly to distinct receptors in brain and pancreatic membranes. The peptide …
and reversibly to distinct receptors in brain and pancreatic membranes. The peptide …
[PDF][PDF] SPECT imaging of striatal dopamine release after amphetamine challenge
In this study, we applied a tracer programmedinfusion technique (20, 21) with the SPECT
D2 receptor probe [†œ-@ I] IBZM (22) to establish a stable baseline for evaluation of the d-…
D2 receptor probe [†œ-@ I] IBZM (22) to establish a stable baseline for evaluation of the d-…
Mixed-affinity binding in humans with 18-kDa translocator protein ligands
11 C-PBR28 PET can detect the 18-kDa translocator protein (TSPO) expressed within
macrophages. However, quantitative evaluation of the signal in brain tissue from donors with …
macrophages. However, quantitative evaluation of the signal in brain tissue from donors with …