User profiles for Renaud Rovera

renaud rovera

Ingénieur d'étude
Verified email at ibcp.fr
Cited by 242

GnRH replacement rescues cognition in Down syndrome

…, V Leysen, M Adamo, I Paiva, R Rovera… - Science, 2022 - science.org
At the present time, no viable treatment exists for cognitive and olfactory deficits in Down
syndrome (DS). We show in a DS model (Ts65Dn mice) that these progressive nonreproductive …

Genetic and pharmacological inactivation of astroglial connexin 43 differentially influences the acute response of antidepressant and anxiolytic drugs

B Portal, S Delcourte, R Rovera, C Lejards… - Acta …, 2020 - Wiley Online Library
Aim Astroglial connexins (Cxs) 30 and 43 are engaged in gap junction and hemichannel
activities. Evidence suggests that these functional entities contribute to regulating …

[HTML][HTML] Chemogenetic activation of prefrontal astroglia enhances recognition memory performance in rat

S Delcourte, A Bouloufa, R Rovera, C Bétry… - Biomedicine & …, 2023 - Elsevier
Prefrontal cortex (PFC) inputs to the hippocampus are supposed to be critical in memory
processes. Astrocytes are involved in several brain functions, such as homeostasis, …

[HTML][HTML] Task-and treatment length–dependent effects of vortioxetine on scopolamine-induced cognitive dysfunction and hippocampal extracellular acetylcholine in …

AL Pehrson, TM Hillhouse, N Haddjeri, R Rovera… - … of Pharmacology and …, 2016 - ASPET
Major depressive disorder (MDD) is a common psychiatric disorder that often features
impairments in cognitive function, and these cognitive symptoms can be important determinants of …

[HTML][HTML] Mucosal Adjuvants Delivered by a Mucoadhesive Patch for Sublingual Administration of Subunit Vaccines

C Monge, C Ayad, AL Paris, R Rovera… - International Journal of …, 2022 - mdpi.com
Among mucosal administration routes for vaccines, the sublingual route has been proven
capable of inducing a potent systemic and mucosal immune response. However, the absence …

[HTML][HTML] Poloxamers have vaccine-adjuvant properties by increasing dissemination of particulate antigen at distant lymph nodes

M Lamrayah, C Phelip, R Rovera, C Coiffier, N Lazhar… - Molecules, 2023 - mdpi.com
Vaccine technology is still facing challenges regarding some infectious diseases, which can
be addressed by innovative drug delivery systems. In particular, nanoparticle-based …

Opposite control of mesocortical and mesoaccumbal dopamine pathways by serotonin2B receptor blockade: Involvement of medial prefrontal cortex serotonin1A …

C Devroye, N Haddjeri, A Cathala, R Rovera… - …, 2017 - Elsevier
Recent studies have shown that serotonin 2B receptor (5-HT 2B R) antagonists exert opposite
facilitatory and inhibitory effects on dopamine (DA) release in the medial prefrontal cortex (…

Differential control of dopamine ascending pathways by serotonin2B receptor antagonists: new opportunities for the treatment of schizophrenia

C Devroye, A Cathala, N Haddjeri, R Rovera… - …, 2016 - Elsevier
Recent studies suggest that the central serotonin 2B receptor (5-HT 2B R) could be an interesting
pharmacological target for treating neuropsychiatric disorders related to dopamine (DA…

The allosteric citalopram binding site differentially interferes with neuronal firing rate and SERT trafficking in serotonergic neurons

…, C Sánchez, Y Martí, S Bahri, R Rovera… - European …, 2016 - Elsevier
Citalopram is a clinically applied selective serotonin re-uptake inhibitor for antidepressant
pharmacotherapy. It consists of two enantiomers, S-citalopram (escitalopram) and R-…

The novel atypical antipsychotic cariprazine demonstrates dopamine D2 receptor‐dependent partial agonist actions on rat mesencephalic dopamine neuronal activity

S Delcourte, CR Ashby Jr, R Rovera… - CNS Neuroscience …, 2018 - Wiley Online Library
Aim Cariprazine, a dopamine D 3 ‐preferring D 3 /D 2 receptor partial agonist, is FDA approved
for the treatment of schizophrenia and acute manic or mixed episodes of bipolar disorder…