User profiles for Raul R. Gainetdinov
Raul R. GainetdinovInstitute of Translational Biomedicine St. Petersburg State University Verified email at spbu.ru Cited by 47015 |
The physiology, signaling, and pharmacology of dopamine receptors
JM Beaulieu, RR Gainetdinov - Pharmacological reviews, 2011 - ASPET
G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the physiological
functions of the catecholaminergic neurotransmitter dopamine, ranging from voluntary …
functions of the catecholaminergic neurotransmitter dopamine, ranging from voluntary …
[HTML][HTML] Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
N-methyl-D-aspartate receptors (NMDARs) represent a subclass of glutamate receptors that
play a critical role in neuronal development and physiology. We report here the generation …
play a critical role in neuronal development and physiology. We report here the generation …
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
…, T Fong, M Fumagalli, RR Gainetdinov… - British journal of …, 2021 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …
Plasma membrane monoamine transporters: structure, regulation and function
The classical biogenic amine neurotransmitters — dopamine, noradrenaline, and 5-hydroxytryptamine
— control a variety of functions including locomotion, autonomic function, …
— control a variety of functions including locomotion, autonomic function, …
Enhanced morphine analgesia in mice lacking β-arrestin 2
The ability of morphine to alleviate pain is mediated through a heterotrimeric guanine
nucleotide binding protein (G protein)–coupled heptahelical receptor (GPCR), the μ opioid …
nucleotide binding protein (G protein)–coupled heptahelical receptor (GPCR), the μ opioid …
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
Transplantation of dopaminergic neurons can potentially improve the clinical outcome of
Parkinson’s disease, a neurological disorder resulting from degeneration of mesencephalic …
Parkinson’s disease, a neurological disorder resulting from degeneration of mesencephalic …
[HTML][HTML] An Akt/β-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
…, S Marion, RJ Lefkowitz, RR Gainetdinov… - Cell, 2005 - cell.com
Dopamine plays an important role in the etiology of schizophrenia, and D2 class dopamine
receptors are the best-established target of antipsychotic drugs. Here we show that D2 class-…
receptors are the best-established target of antipsychotic drugs. Here we show that D2 class-…
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
Morphine is a powerful pain reliever, but also a potent inducer of tolerance and dependence.
The development of opiate tolerance occurs on continued use of the drug such that the …
The development of opiate tolerance occurs on continued use of the drug such that the …
Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity
The mechanism by which psychostimulants act as calming agents in humans with attention-deficit
hyperactivity disorder (ADHD) or hyperkinetic disorder is currently unknown. Mice …
hyperactivity disorder (ADHD) or hyperkinetic disorder is currently unknown. Mice …
Desensitization of G protein–coupled receptors and neuronal functions
▪ Abstract G protein–coupled receptors (GPCRs) have proven to be the most highly favorable
class of drug targets in modern pharmacology. Over 90% of nonsensory GPCRs are …
class of drug targets in modern pharmacology. Over 90% of nonsensory GPCRs are …