Medetomidine--a novel alpha 2-adrenoceptor agonist: a review of its pharmacodynamic effects.

…, R Virtanen, E Macdonald, R Lammintausta… - Progress in neuro …, 1989 - europepmc.org
1. The pharmacodynamic effects of medetomidine, a novel alpha 2-adrenoceptor agonist,
are reviewed. 2. In receptor binding experiments, and in isolated organ preparations …

Pharmacokinetic aspects of l‐deprenyl (selegiline) and its metabolites*

…, MI Anttila, RAS Lammintausta - Clinical Pharmacology …, 1994 - Wiley Online Library
… Heinonen EH, Anttila MI, Lammintausta RAS. Pharrnacokinetics and clinical pharmacology
of … Heinonen E, LaIpmintausta R. A review of the pharmacology of selegiline. Acta Neurol …

A review of the pharmacology of selegiline

EH Heinonen, R Lammintausta - Acta Neurologica …, 1991 - Wiley Online Library
Selegiline (1‐deprenyl) is an irreversible inhibitor of monoamine oxidase (MAO) type B.
Because in the human brain, dopamine is metabolised mainly by MAO‐B, selegiline increases …

Effects of ospemifene, a novel SERM, on hormones, genital tract, climacteric symptoms, and quality of life in postmenopausal women: a double-blind, randomized trial

…, J Heikkinen, K Halonen, J Komi, R Lammintausta… - Menopause, 2003 - journals.lww.com
Objective Ospemifene, a novel selective estrogen receptor modulator, shows a potential for
prevention and treatment of osteoporosis in postmenopausal women. We studied the effects …

Effects of ospemifene and raloxifene on biochemical markers of bone turnover in postmenopausal women

…, M Tuppurainen, K Halonen, R Lammintausta… - Journal of bone and …, 2006 - Springer
Ospemifene is a novel selective estrogen receptor modulator (SERM) that is initially being
developed for the treatment of vaginal atrophy in postmenopausal women. However, it also …

Effects of ospemifene, a novel SERM, on biochemical markers of bone turnover in healthy postmenopausal women

…, M Rutanen, K Halonen, R Lammintausta… - Gynecological …, 2004 - Taylor & Francis
Ospemifene is a novel selective estrogen receptor modulator (SERM). Here we studied the
effects of ospemifene on bone turnover in postmenopausal women. This was a randomized, …

Effect of selegiline on mortality in patients with Parkinson's disease: a meta-analysis

…, H Przuntek, EH Heinonen, O Kilkku, R Lammintausta… - Neurology, 1998 - AAN Enterprises
Introduction: The Parkinson's Disease Research Group of the United Kingdom (PDRG-UK)
reported increased mortality in PD patients treated with levodopa plus selegiline compared …

Change in hormones reflecting sympathetic activity in the Finnish sauna.

R Lammintausta, E Syvälahti… - Annals of clinical …, 1976 - europepmc.org
The effects of the high temperature (80-120 degrees C) of the Finnish Sauna bath on the
concentrations of growth hormone, immunoreactive insulin and renin activity in plasma, on …

Effects of ospemifene, a novel SERM, on vascular markers and function in healthy, postmenopausal women

…, K Halonen, R Lassila, R Lammintausta… - Menopause, 2003 - journals.lww.com
Objective Ospemifene, a novel selective estrogen receptor modulator (SERM), shows
promise for bone preservation in postmenopausal women. This study examined the effects of …

Vaginal effects of ospemifene in the ovariectomized rat preclinical model of menopause

M Unkila, S Kari, E Yatkin, R Lammintausta - The Journal of Steroid …, 2013 - Elsevier
Ospemifene is a unique tissue-selective estrogen agonist/antagonist (also known as a selective
estrogen receptor modulator [SERM]) with demonstrated efficacy in Phase 3 studies of …