In the past few years, inflammation has emerged as a major driving force of atherosclerotic
lesion development. It is now well-established that from early lesion to vulnerable plaque …

Atherosclerosis is a multifactorial highly-complex disease with numerous etiologies that
work synergistically to promote lesion development. The ability to develop preventive and …

… Bernhagen and R. Kleemann, unpublished). … We are grateful to our colleagues for
participation in the studies and their helpful discussions: R. Bucala, H. Brunner, A. …

The cytokine macrophage migration inhibitory factor (MIF) plays a critical role in inflammatory
diseases and atherogenesis. We identify the chemokine receptors CXCR2 and CXCR4 as …

… Kleemann, R. et al. Disulfide analysis reveals a role for macrophage migration … Angel
for the pBAT-c-Jun and pRSV-c-Jun constructs; and R. Bucala for … Robert Kleemann …

Background and aims The recently developed histological scoring system for non-alcoholic
fatty liver disease (NAFLD) by the NASH Clinical Research Network (NASH-CRN) has been …

The molecular mechanism of action of macrophage migration inhibitory factor (MIF), a cytokine
with a critical role in the immune and inflammatory response, has not yet been identified. …

Background— Atherosclerosis is a chronic inflammatory response of the arterial wall to injury.
Macrophage migration inhibitory factor (MIF), a cytokine with potent inflammatory functions…

OBJECTIVE: Polyphenols such as quercetin may exert several beneficial effects, including
those resulting from anti-inflammatory activities, but their impact on cardiovascular health is …

Atherosclerotic plaques develop in the inner intimal layer of arteries and can cause heart
attacks and strokes 1 . As plaques lack innervation, the effects of neuronal control on …