Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells

…, R Estephan, RB Silver, D Mochly-Rosen, R Levi - Circulation, 2010 - Am Heart Assoc
… A, Coronary overflow of renin and norepinephrine and duration of reperfusion arrhythmias
(VT/VF) in I/R (n=6) and I/R preceded by IPC (n=8) or I/R preceded by IPC in the presence of …

Solution-state molecular structure of apo and oleate-liganded liver fatty acid-binding protein

Y He, X Yang, H Wang, R Estephan, F Francis… - Biochemistry, 2007 - ACS Publications
Rat liver fatty acid-binding protein (LFABP) is distinctive among intracellular lipid-binding
proteins (iLBPs): more than one molecule of long-chain fatty acid and a variety of diverse …

Mast cell renin and a local renin–angiotensin system in the airway: role in bronchoconstriction

A Veerappan, AC Reid, R Estephan… - Proceedings of the …, 2008 - National Acad Sciences
… ANG II receptors are also expressed in lung tissue, with the ANG II type 1 receptor (AT 1 R)
subtype found on bronchial smooth muscle cells (9) and ANG II type 2 receptor (AT 2 R) …

[PDF][PDF] The influence of water on the nanomechanical behavior of the plant biopolyester cutin as studied by AFM and solid-state NMR

AN Round, B Yan, S Dang, R Estephan, RE Stark… - Biophysical …, 2000 - cell.com
… The indentation is related to the surface area A of the contact between a conical tip of radius
R and a flat sample … Measurements taken from over 40 tips produced an average value of R

Mast cells are required for the development of renal fibrosis in the rodent unilateral ureteral obstruction model

…, R Mora, JA Brazin, R Estephan… - American Journal …, 2012 - journals.physiology.org
… multiple effects via activation of AT 1 R, such as vasoconstriction and fibroblast stimulation
(45). It is speculated that ANG II activation of AT 1 R on neighboring fibroblasts stimulates TGF-…

Externalization of phosphatidylserine may not be an early signal of apoptosis in neuronal cells, but only the phosphatidylserine‐displaying apoptotic cells are …

T Adayev, R Estephan, S Meserole… - Journal of …, 1998 - Wiley Online Library
… Adayev and R. Estephan contributed equally to this study. Abbreviations used: AcDEVD-AMC.
acetyl-Asp-Glu-Val-Aspamino-4-methylcouniarin; CPP32, caspase-3; DMEM. …

[HTML][HTML] MicroRNA regulation of T-cell exhaustion in cutaneous T cell lymphoma

Z Han, RJ Estephan, X Wu, C Su, YC Yuan… - Journal of Investigative …, 2022 - Elsevier
… The subsequent data analysis was performed using the Seurat package and R scripts.
Normalized and scaled data were clustered using the top principal components of highly variable …

Biosynthesis and NMR Analysis of a 73-Residue Domain of a Saccharomyces cerevisiae G Protein-Coupled Receptor

R Estephan, J Englander, B Arshava, KL Samples… - Biochemistry, 2005 - ACS Publications
The yeast Saccharomyces cerevisiae α-factor pheromone receptor (Ste2p) was used as a
model G protein-coupled receptor (GPCR). A 73-mer multidomain fragment of Ste2p (residues …

Histamine H3-receptor signaling in cardiac sympathetic nerves: Identification of a novel MAPK-PLA2-COX-PGE2-EP3R pathway

R Levi, N Seyedi, U Schaefer, R Estephan… - Biochemical …, 2007 - Elsevier
… Our findings imply that an EP 3 R Gβγ i -induced … 3 R-mediated attenuation of NE exocytosis
elicited by H 3 R activation. Conceivably, activation of the Gβγ i subunit of H 3 R and EP 3 R

Sexual conjugation in yeast: A paradigm to study G‐protein‐coupled receptor domain structure

F Naider, R Estephan, J Englander… - Peptide Science …, 2004 - Wiley Online Library
The yeast Saccharomyces cerevisiae undergoes cell fusion during sexual conjugation to form
diploid cells. The haploids participating in this process signal each other through secreted …