Gastric and intestinal transit in rats measured by a radioactive test meal

RA Purdon, P Bass - Gastroenterology, 1973 - Elsevier
Measurements of the passage of a Ba 133 SO 4 test meal through the stomach and small
intestine of the rat were made under various test conditions and after drug treatment. These …

Prolonged administration of atropine or histamine in a silicone rubber implant

P Bass, RA Purdon, JN Wiley - Nature, 1965 - nature.com
IN the use of drugs, it is often desirable to maintain a constant blood and tissue concentration
of chemical for prolonged periods. Several attempts to avoid the ‘sawtooth’ oscillations of …

Gastric antisecretory and other pharmacologic studies on 2, 2'-bipyridine

P Bass, RA Purdon, MA Patterson, DE Butler - Journal of Pharmacology and …, 1966 - ASPET
2,2'-Bipyridine (CI-588) was evaluated for gastric antisecretory and other pharmacologic
activities. It decreased secretion volumes and hydrogen ion and pepsin outputs in the 4-…

Developments in non-anticholinergic anti-ulcer agents

DE Butler, RA Purdon, P Bass - The American Journal of Digestive …, 1970 - Springer
Since the introduction of belladonna alkaloids, drugs blocking the cholinergic nervous system
have dominated therapeutics for peptic ulcer. Until recently, the only modification of this …

Gastric antisecretory and other pharmacologic studies of 3-methylamino-2, 1-benzisothiazole

P Bass, RA Purdon, MA Patterson - Journal of Pharmacology and …, 1966 - ASPET
3-Methylamino-2,1-benzisothiazole (CI-624) and its HC1 salt (CI-624 HC1) were studied in
rats and dogs for their effects on gastric secretion and other biologic parameters. In the rat, CI-…

[CITATION][C] Effect of chelators and divalent cations on gastric secretion in the rat.

…, DE Butler, MA Patterson, RA Purdon - … de Pharmacodynamie et …, 1967 - europepmc.org
Purdon RA … Butler DE, Purdon RA, Bass P …

[CITATION][C] Stabilities and selectivities of alkali-metal complexes of tetraethylene glycol dimethyl ether in methanol and acetonitrile

…, RAB BANNARD, JG Purdon - Journal of physical …, 1988 - pascal-francis.inist.fr
Stabilities and selectivities of alkali-metal complexes of tetraethylene glycol dimethyl ether
in methanol and acetonitrile CNRS Inist Pascal-Francis CNRS Pascal and Francis …

A simple method to investigate the inhibitory effects of drugs on gastric emptying in the mouse in vivo

CK Yeung, JR McCurrie, D Wood - Journal of pharmacological and …, 2001 - Elsevier
Introduction: The aim was to develop a simple method to study modification of gastric motility
in the mouse in vivo. Methods: Mice were fed a hydrated diet in which the fluid content of …

The roles of insulin and catecholamines in the glucoregulatory response during intense exercise and early recovery in insulin-dependent diabetic and control subjects

C Purdon, M Brousson, SL Nyveen… - The Journal of …, 1993 - academic.oup.com
… with a marked stimulation of glucose production (Ra), a somewhat smaller increment in its
… We infer that the catecholamine increments and decrements are the prime regulators of Ra (…

Electroencephalogram signatures of loss and recovery of consciousness from propofol

PL Purdon, ET Pierce, EA Mukamel… - Proceedings of the …, 2013 - National Acad Sciences
Unconsciousness is a fundamental component of general anesthesia (GA), but anesthesiologists
have no reliable ways to be certain that a patient is unconscious. To develop EEG …