User profiles for R. P. Markus
Regina Pekelmann MarkusProfessor of Physiology, University of São Paulo Verified email at usp.br Cited by 7014 |
Update on melatonin receptors: IUPHAR Review 20
…, ML Dubocovich, RP Markus… - British journal of …, 2016 - Wiley Online Library
Melatonin receptors are seven transmembrane‐spanning proteins belonging to the GPCR
superfamily. In mammals, two melatonin receptor subtypes exist ‐ MT 1 and MT 2 ‐ encoded …
superfamily. In mammals, two melatonin receptor subtypes exist ‐ MT 1 and MT 2 ‐ encoded …
Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation
The hormone melatonin produced by the pineal gland during the daily dark phase regulates
a variety of biological processes in mammals. The aim of this study was to determine the …
a variety of biological processes in mammals. The aim of this study was to determine the …
Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites.
* Departamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, São
Paulo 05508-90, Brasil† Dipartimento di Scienze Biomediche Sperimentali, Centro CNR ‘…
Paulo 05508-90, Brasil† Dipartimento di Scienze Biomediche Sperimentali, Centro CNR ‘…
Immune‐pineal axis–acute inflammatory responses coordinate melatonin synthesis by pinealocytes and phagocytes
Melatonin is well known for its circadian production by the pineal gland, and there is a growing
body of data showing that it is also produced by many other cells and organs, including …
body of data showing that it is also produced by many other cells and organs, including …
[HTML][HTML] NF-κB drives the synthesis of melatonin in RAW 264.7 macrophages by inducing the transcription of the arylalkylamine-N-acetyltransferase (AA-NAT) gene
We demonstrate that during inflammatory responses the nuclear factor kappa B (NF-κB)
induces the synthesis of melatonin by macrophages and that macrophage-synthesized …
induces the synthesis of melatonin by macrophages and that macrophage-synthesized …
The immune-pineal axis: a shuttle between endocrine and paracrine melatonin sources
… 6 Barbosa EJM, Ferreira ZS, Markus RP: Purinergic and … L, Farsky SH, Ferreira ZS, Markus
RP: Melatonin inhibits nitric oxide … 21 Tamura EK, Silva CL, Markus RP: Melatonin inhibits …
RP: Melatonin inhibits nitric oxide … 21 Tamura EK, Silva CL, Markus RP: Melatonin inhibits …
Pineal melatonin and the innate immune response: the TNF‐α increase after cesarean section suppresses nocturnal melatonin production
…, MMS Carneiro‐Sampaio, RP Markus - Journal of pineal …, 2007 - Wiley Online Library
The nocturnal surge of melatonin is the endocrine expression of the circadian system and is
essential for organizing the timing of various endogenous processes. Previous works …
essential for organizing the timing of various endogenous processes. Previous works …
[HTML][HTML] Immune-pineal axis: nuclear factor κB (NF-κB) mediates the shift in the melatonin source from pinealocytes to immune competent cells
RP Markus, E Cecon, MA Pires-Lapa - International journal of molecular …, 2013 - mdpi.com
Pineal gland melatonin is the darkness hormone, while extra-pineal melatonin produced by
the gonads, gut, retina, and immune competent cells acts as a paracrine or autocrine …
the gonads, gut, retina, and immune competent cells acts as a paracrine or autocrine …
Effect of TNF‐α on the melatonin synthetic pathway in the rat pineal gland: basis for a 'feedback' of the immune response on circadian timing
PACM Fernandes, E Cecon, RP Markus… - Journal of pineal …, 2006 - Wiley Online Library
A retino‐hypothalamic‐sympathetic pathway drives the nocturnal surge of pineal melatonin
production that determines the synchronization of pineal function with the environmental light/…
production that determines the synchronization of pineal function with the environmental light/…
TLR4 and CD14 receptors expressed in rat pineal gland trigger NFKB pathway
…, ZS Ferreira, RP Markus - Journal of pineal …, 2010 - Wiley Online Library
Nuclear factor‐kappa B (NFKB), a pivotal player in inflammatory responses, is constitutively
expressed in the pineal gland. Corticosterone inhibits pineal NFKB leading to an …
expressed in the pineal gland. Corticosterone inhibits pineal NFKB leading to an …