Functional interaction of chloroplast SRP/FtsY with the ALB3 translocase in thylakoids: substrate not required

M Moore, RL Goforth, H Mori, R Henry - The Journal of cell biology, 2003 - rupress.org
Integration of thylakoid proteins by the chloroplast signal recognition particle (cpSRP)
posttranslational transport pathway requires the cpSRP, an SRP receptor homologue (cpFtsY), …

Hydrophobic coupling of lipid bilayer energetics to channel function

RL Goforth, AK Chi, DV Greathouse… - The Journal of general …, 2003 - rupress.org
The hydrophobic coupling between membrane-spanning proteins and the lipid bilayer core
causes the bilayer thickness to vary locally as proteins and other “defects” are embedded in …

Using hapten design to discover therapeutic monoclonal antibodies for treating methamphetamine abuse

EC Peterson, M Gunnell, Y Che, RL Goforth… - … of Pharmacology and …, 2007 - ASPET
When generating monoclonal antibodies (mAb) against small molecules, the chemical
composition and molecular orientation of the drug-like hapten on the antigen is a crucial …

Class II correction: Extraction or nonextraction?

JL Vaden, RA Williams, RL Goforth - American Journal of Orthodontics and …, 2018 - Elsevier
Highlights • Facial balance and harmony are major goals of Class II malocclusion correction.
• A patient with a moderate-to-low MP angle and Class II can be treated with premolar …

[HTML][HTML] A dynamic cpSRP43-Albino3 interaction mediates translocase regulation of chloroplast signal recognition particle (cpSRP)-targeting components

…, A Daily, TKS Kumar, RL Henry, RL Goforth - Journal of biological …, 2010 - ASBMB
The chloroplast signal recognition particle (cpSRP) and its receptor, chloroplast FtsY (cpFtsY),
form an essential complex with the translocase Albino3 (Alb3) during post-translational …

[HTML][HTML] Regulation of the GTPase cycle in post-translational signal recognition particle-based protein targeting involves cpSRP43

RL Goforth, EC Peterson, J Yuan, MJ Moore… - Journal of Biological …, 2004 - ASBMB
The chloroplast signal recognition particle consists of a conserved 54-kDa GTPase and a
novel 43-kDa chromodomain protein (cpSRP43) that together bind light-harvesting chlorophyll …

[HTML][HTML] ATP stimulates signal recognition particle (SRP)/FtsY-supported protein integration in chloroplasts

J Yuan, A Kight, RL Goforth, M Moore… - Journal of Biological …, 2002 - ASBMB
The signal recognition particle (SRP) and its receptor (FtsY in prokaryotes) are essential for
cotranslational protein targeting to the endoplasmic reticulum in eukaryotes and the …

[HTML][HTML] The Membrane-binding Motif of the Chloroplast Signal Recognition Particle Receptor (cpFtsY) Regulates GTPase Activity*♦

…, D Fologea, TKS Kumar, RL Henry, RL Goforth - Journal of Biological …, 2009 - ASBMB
The chloroplast signal recognition particle (cpSRP) and its receptor (cpFtsY) function in
thylakoid biogenesis to target integral membrane proteins to thylakoids. Unlike cytosolic SRP …

[HTML][HTML] Regulation of structural dynamics within a signal recognition particle promotes binding of protein targeting substrates

…, P Sharma, RL Goforth, TKS Kumar, RL Henry… - Journal of Biological …, 2015 - ASBMB
Protein targeting is critical in all living organisms and involves a signal recognition particle (SRP),
an SRP receptor, and a translocase. In co-translational targeting, interactions among …

[HTML][HTML] Renal vascular sclerosis is associated with inherited thrombophilias

RL Goforth, H Rennke, S Sethi - Kidney international, 2006 - Elsevier
Vascular sclerosis is often seen in renal biopsies. It is usually associated with diabetes
mellitus, hypertension, smoking, etc. However, whether inherited thrombophilic states such as …