User profiles for R. J. Hansen

Ryan J. Hansen

Eli Lilly and Company
Verified email at lilly.com
Cited by 2075

Antibody pharmacokinetics and pharmacodynamics

ED Lobo, RJ Hansen, JP Balthasar - Journal of pharmaceutical sciences, 2004 - Elsevier
Hansen 1 , Joseph P. Balthasar 2 … A similar model has been employed by Hansen and
Balthasar48 to characterize antibody‐mediated thrombocytopenia in rats. …

[HTML][HTML] Estrogen induction of VLDLy assembly in egg-laying hens

RL Walzem, RJ Hansen, DL Williams… - The Journal of nutrition, 1999 - Elsevier
The yolk of a 60-g chicken egg contains 6 g of triacylglycerols transported to the oocyte from
the liver of the laying hen in apolipoprotein (apo) B–containing particles. With the onset of …

Some mechanical tests on the lumbosacral spine with particular reference to the intervertebral discs: a preliminary report

T Brown, RJ Hansen, AJ Yorra - JBJS, 1957 - journals.lww.com
The investigations reported here represent an effort to explore the possibilities of obtaining
quantitative data on the mechanical properties of the lumbosacral spine by applying to fresh …

[HTML][HTML] Catechin is present as metabolites in human plasma after consumption of red wine

…, JB German, RL Walzem, RJ Hansen… - The Journal of …, 1999 - Elsevier
Flavonoids are components of fruits, vegetables and wines. An abundance of flavonoids in
the diet is correlated with reduced heart disease mortality, suggesting that they act as …

Avian fatty liver hemorrhagic syndrome: a comparative review.

RJ Hansen, RL Walzem - Advances in Veterinary Science and …, 1993 - europepmc.org
Metabolic fatty liver syndromes occur in a variety of species including chickens, humans,
cows, and cats. Both energy excess and deficit appear to initiate the accumulation of liver fat. …

STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious

…, S Aryal, JM Mulcahy Levy, SP Fosmire, RJ Hansen… - Cancer research, 2014 - AACR
Autophagy is a protein and organelle degradation pathway that is involved in diverse diseases,
including cancer. Recent evidence suggests that autophagy is a cell survival mechanism …

Development of selective colorimetric probes for hydrogen sulfide based on nucleophilic aromatic substitution

LA Montoya, TF Pearce, RJ Hansen… - The Journal of …, 2013 - ACS Publications
Hydrogen sulfide is an important biological signaling molecule and an important
environmental target for detection. A major challenge in developing H 2 S detection methods is …

Intravenous immunoglobulin mediates an increase in anti-platelet antibody clearance via the FcRn receptor

RJ Hansen, JP Balthasar - Thrombosis and haemostasis, 2002 - thieme-connect.com
We have recently shown that intravenous immunoglobulin (IVIG) therapy leads to an increased
rate of anti-platelet antibody clearance in an animal model of immune thrombocytopenia. …

[HTML][HTML] Combination treatment of the oral CHK1 inhibitor, SRA737, and low-dose gemcitabine enhances the effect of programmed death ligand 1 blockade by …

…, CA Stewart, Y Fan, L Shen, RJ Hansen… - Journal of Thoracic …, 2019 - Elsevier
Introduction Despite the enthusiasm surrounding cancer immunotherapy, most SCLC
patients show very modest response to immune checkpoint inhibitor monotherapy treatment. …

Effects of intravenous immunoglobulin on platelet count and antiplatelet antibody disposition in a rat model of immune thrombocytopenia

RJ Hansen, JP Balthasar - Blood, The Journal of the American …, 2002 - ashpublications.org
Experiments were conducted to investigate the effects of intravenous immunoglobulin (IVIG)
in a rat model of immune thrombocytopenia (ITP). Rats were pretreated with 0 to 2 g/kg IVIG …