Clinical pharmacokinetics of verapamil

SR Hamann, RA Blouin, RG McAllister - Clinical pharmacokinetics, 1984 - Springer
Verapamil is widely used in the treatment of supraventricular tachyarrhythmias as well as for
hypertension and control of symptoms in angina pectoris. Unlike other calcium antagonists, …

A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients

WJ Rosoff, JS Urbach, MA Esrick, RG McAllister… - Nature …, 2004 - nature.com
Axonal chemotaxis is believed to be important in wiring up the developing and regenerating
nervous system, but little is known about how axons actually respond to molecular gradients…

How to run molecular dynamics simulations on electrospray droplets and gas phase proteins: Basic guidelines and selected applications

L Konermann, H Metwally, RG McAllister, V Popa - Methods, 2018 - Elsevier
The ability to transfer intact proteins and protein complexes into the gas phase by electrospray
ionization (ESI) has opened up numerous mass spectrometry (MS)-based avenues for …

Pharmacokinetics of calcium-entry blockers

RG McAllister Jr, SR Hamann, RA Blouin - The American Journal of …, 1985 - Elsevier
McAllister RG, Tan TG. Effect of hypothermia on drug metabolism: in vitro studies with …
Hamann SR, McAllister RG. Measurement of nifedipine in plasma by gasliquid chromatography …

Nifedipine kinetics and bioavailability after single intravenous and oral doses in normal subjects

…, PJ Bryant, DA Graves, RG McAllister - The Journal of …, 1983 - Wiley Online Library
Nifedipine kinetics have not been described in clinically relevant detail because of difficulties
in formulating a stable preparation for intravenous use and lack of a specific and sensitive …

Release of native-like gaseous proteins from electrospray droplets via the charged residue mechanism: insights from molecular dynamics simulations

RG McAllister, H Metwally, Y Sun… - Journal of the American …, 2015 - ACS Publications
The mechanism whereby gaseous protein ions are released from charged solvent droplets
during electrospray ionization (ESI) remains a matter of debate. Also, it is unclear to what …

Collision-induced dissociation of electrosprayed protein complexes: an all-atom molecular dynamics model with mobile protons

V Popa, DA Trecroce, RG McAllister… - The Journal of …, 2016 - ACS Publications
Electrospray ionization mass spectrometry (ESI-MS) has become an indispensable technique
for examining noncovalent protein complexes. Collision-induced dissociation (CID) of …

Oral insulin product hexyl-insulin monoconjugate 2 (HIM2) in type 1 diabetes mellitus: the glucose stabilization effects of HIM2

…, JG Still, G Kosutic, RG McAllister - Diabetes technology & …, 2002 - liebertpub.com
This study was designed to determine plasma glucose and insulin levels after administration
of three escalating doses of the oral insulin product hexyl-insulin monoconjugate 2 (HIM2) …

Fulminant beriberi heart disease with lactic acidosis: presentation of a case with evaluation of left ventricular function and review of pathophysiologic mechanisms.

…, HG Hanley, D Stultz, MR Jones, RG McAllister - Circulation, 1978 - Am Heart Assoc
Cardiac beriberi is considered a rare disease in western society. A patient with fulminant
Shoshin-type beriberi was studied in the acute phase and found to have severe metabolic …

Exploring the mechanism of salt-induced signal suppression in protein electrospray mass spectrometry using experiments and molecular dynamics simulations

H Metwally, RG McAllister, L Konermann - Analytical chemistry, 2015 - ACS Publications
Protein analyses by electrospray ionization (ESI) mass spectrometry can suffer from
interferences caused by nonvolatile salts. The mechanistic basis of this effect remains to be fully …