Dry eye has gained recognition as a public health problem given its prevalence, morbidity,
and cost implications. Dry eye can have a variety of symptoms including blurred vision, …

Dry eye is a common, multifactorial disease currently diagnosed by a combination of
symptoms and signs. Its epidemiology and clinical presentation have many similarities with …

Laser in-situ keratomileusis (LASIK) is a commonly performed surgical procedure used to
correct refractive error. LASIK surgery involves cutting a corneal flap and ablating the stroma …

Background Bronchial hyperresponsiveness, a risk factor for asthma, consists of a
heightened bronchoconstrictor response to a variety of stimuli. The condition has a heritable …

Background Colorectal cancer occurs in approximately 150,000 people each year in the United
States. Prognostic assessment influences the treatment of patients with colorectal cancer…

Genetics studies of total serum IgE levels were performed since high IgE levels correlate
with clinical expression of allergy and asthma. Families ascertained through a parent with …

Background: Bronchial asthma is a chronic inflammatory disease associated with genetic
components. Recently IL-9 has been reported as a candidate gene for asthma and to be …

… C., Nicolaides NC, Holroyd KL, Levitt RCInterleukin-9 promotes allergen-induced
eosinophilic inflammation and airway hyperresponsiveness in transgenic mice. Am. J. …

Asthma is a complex heritable inflammatory disorder of the airways associated with clinical
signs of atopy and bronchial hyperresponsiveness. Recent studies localized a major gene for …

… & Levitt, RC Structure and DNA sequence of the mouse MnSOD gene. Mamm. Genome 6, …
Elston, Rc The genetic analysis of quantitative trait differences between two homozygous lines…