Glycogen synthase kinase 3: a drug target for CNS therapies

RV Bhat, SL Budd Haeberlein… - Journal of …, 2004 - Wiley Online Library
Glycogen synthase kinase3 (GSK3) is emerging as a prominent drug target in the CNS. The
most exciting of the possibilities of GSK3 lies within the treatment of Alzheimer's disease (AD…

Mycotoxins in foods-occurrence, health & economic significance & food control measures

S Vasanthi, RV Bhat - Indian Journal of Medical Research, 1998 - search.proquest.com
… Shetty PH, Bhat RV. Effect of unleavened Indian bread and porridge preparation on
fumonisin BI content in naturally contaminated maize. Food Addit Contam 1998 (in press). …

Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.

JS Jung, RV Bhat, GM Preston… - Proceedings of the …, 1994 - National Acad Sciences
The aquaporins transport water through membranes of numerous tissues, but the molecular
mechanisms for sensing changes in extracellular osmolality and regulating water balance in …

Workgroup report: public health strategies for reducing aflatoxin exposure in developing countries

…, M Banziger, RV Bhat… - Environmental …, 2006 - ehp.niehs.nih.gov
Consecutive outbreaks of acute aflatoxicosis in Kenya in 2004 and 2005 caused > 150
deaths. In response, the Centers for Disease Control and Prevention and the World Health …

Hepatitis due to aflatoxicosis: an outbreak in western India

K Krishnamachari, V Nagarajan, RV Bhat, TBG Tilak - The Lancet, 1975 - Elsevier
Parts of Western India have experienced an outbreak of hepatitis affecting man and dogs
and characterised by jaundice, rapidly developing ascites, portal hypertension, and a high …

The conundrum of GSK3 inhibitors: is it the dawn of a new beginning?

RV Bhat, U Andersson, S Andersson… - Journal of …, 2018 - content.iospress.com
Spanning over three decades of extensive drug discovery research, the efforts to develop a
potent and selective GSK3 inhibitor as a therapeutic for the treatment of type 2 diabetes, …

Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3β in cellular and animal models of neuronal degeneration

RV Bhat, J Shanley, MP Correll… - Proceedings of the …, 2000 - National Acad Sciences
Inactivation of glycogen synthase kinase-3β (GSK3β) by S 9 phosphorylation is implicated
in mechanisms of neuronal survival. Phosphorylation of a distinct site, Y 216 , on GSK3β is …

Outbreak of trichothecene mycotoxicosis associated with consumption of mould-damaged wheat products in Kashmir Valley, India

RV Bhat, Y Ramakrishna, SR Beedu, KL Munshi - The Lancet, 1989 - Elsevier
… Ramakrishna Y, Bhat RV. Comparison of different spray reagents for detection of …
Krishnamachari KAVR, Bhat RV, Nagarajan V, Tilak TBG Hepatitis due to aflatoxicosis: an outbreak …

Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement

PF Worley, RV Bhat, JM Baraban… - Journal of …, 1993 - Soc Neuroscience
Recent studies suggest a role for rapid induction of transcription factors in stimulus-induced
neuronal plasticity in the mammalian brain. Synaptic activation of transcription factors has …

A foodborne disease outbreak due to the consumption of moldy sorghum and maize containing fumonisin mycotoxins

RV Bhat, PH Shetty, RP Amruth… - Journal of toxicology …, 1997 - Taylor & Francis
Background: Unseasonal rains beginning in 1995 damaged the maize and sorghum crops
harvested in a few villages of the Deccan plateau in India. Human consumption of those …