… Comparable ‘protein concentrations -of the subcellular fractions were obtained bv dilutinrr
the 280,000 R supematant 1:2 (v/v) (0.26 r 0.02 mg/mL),concentrating the 280,OOOg pellet 3-…

The reactive intermediate formed by 5-lipoxygenase metabolism of arachidonic acid,
leukotriene A 4 , is known to be released from cells and subsequently taken up by other cells for …

Recent studies have suggested that part of the vasorelaxation caused by nifedipine, a 1,4-dihydropyridine
Ca 2+ antagonist, depends on the endothelium. To study the effect of …

Amplified chemiluminescence (CL) detects most sensitively biologically important reactive
oxygen species (ROS) which are generated by phagocytes by the respiratory burst permitting …

Perfusion of the isolated rabbit heart with 5 x 10(6) human polymorphonuclear leukocytes,
under recirculating conditions (50 ml), and challenge with A-23187 (0.5 microM) caused an …

Five-lipoxygenase (5-LOX) inhibition is gaining increasing importance as a novel approach
to therapy of allergic asthma and other inflammatory diseases. Presently, two types of …

Prostacyclin (PGI2) production by thrombin- and bradykinin-stimulated bovine aortic endothelial
cells (BAEC) and human umbilical vein endothelial cells (HUVEC) was related to the …

A morphological study of kidneys of 101 dogs with and without clinical signs of renal disease
was done. In 90% of the dogs there was morphologic evidence of glomerulopathy. Types of …

The levels of serum interleukin-6 (IL-6) were measured during the course of adjuvant arthritis
(FAA) in male Lewis rats. In the course of the disease serum IL-6 levels increase with a …

Formation of eicosanoids is a special mode of cell communication whereby produc tion of
eicosanoids by mixed cell populations differs from that expected from each individual cell. …