Carvedilol prevents doxorubicin-induced free radical release and apoptosis in cardiomyocytes in vitro
P Spallarossa, S Garibaldi, P Altieri, P Fabbi… - Journal of molecular and …, 2004 - Elsevier
The clinical use of doxorubicin, a highly active anticancer drug, is limited by its severe
cardiotoxic side effects. Increased oxidative stress and apoptosis have been implicated in the …
cardiotoxic side effects. Increased oxidative stress and apoptosis have been implicated in the …
Polycystic ovary syndrome is a risk factor for type 2 diabetes: results from a long-term prospective study
A Gambineri, L Patton, P Altieri, U Pagotto, C Pizzi… - Diabetes, 2012 - Am Diabetes Assoc
Polycystic ovary syndrome (PCOS) recently has been identified as a risk factor associated
with type 2 diabetes. However, the evidence derives from cross-sectional observational …
with type 2 diabetes. However, the evidence derives from cross-sectional observational …
[HTML][HTML] Adipose tissue immune response: novel triggers and consequences for chronic inflammatory conditions
…, P Fabbi, C Brunelli, P Spallarossa, P Altieri… - Inflammation, 2014 - Springer
Adipose tissue inflammation mediates the association between excessive body fat
accumulation and several chronic inflammatory diseases. A high prevalence of obesity-associated …
accumulation and several chronic inflammatory diseases. A high prevalence of obesity-associated …
Matrix metalloproteinase-2 and-9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD (P) H oxidase
P Spallarossa, P Altieri, S Garibaldi… - Cardiovascular …, 2006 - academic.oup.com
Objective: Dysregulation of myocardial metalloproteinases (MMPs) is now regarded as an
early contributory mechanism for the initiation and progression of heart failure. Doxorubicin is …
early contributory mechanism for the initiation and progression of heart failure. Doxorubicin is …
Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2
P Spallarossa, P Altieri, C Aloi… - American Journal …, 2009 - journals.physiology.org
Low or high doses of doxorubicin induce either senescence or apoptosis, respectively, in
cardiomyocytes. The mechanism by which different doses of doxorubicin may induce different …
cardiomyocytes. The mechanism by which different doses of doxorubicin may induce different …
Dietary habits and their relationship with hormones and metabolism in overweight and obese women with polycystic ovary syndrome
P Altieri, C Cavazza, F Pasqui, AM Morselli… - Clinical …, 2013 - Wiley Online Library
Objective This study investigates energy intake, macronutrient composition and habitual food
choices in overweight/obese women with polycystic ovary syndrome ( PCOS ) and controls …
choices in overweight/obese women with polycystic ovary syndrome ( PCOS ) and controls …
CD14CD16 monocyte subset levels in heart failure patients
…, S Garibaldi, G Ghigliotti, P Fabbi, P Altieri… - Disease …, 2010 - content.iospress.com
Our aim was to define the distribution of monocyte subsets in a cohort of congestive heart
failure (CHF) patients, to verify whether increased severity of CHF is linked to the expansion of …
failure (CHF) patients, to verify whether increased severity of CHF is linked to the expansion of …
Effects of testosterone undecanoate administered alone or in combination with letrozole or dutasteride in female to male transsexuals
…, F Armillotta, A Costantino, P Altieri… - The journal of sexual …, 2008 - academic.oup.com
Introduction Testosterone undecanoate (TU) has potential as androgen therapy for ovariectomized
female to male (FtM) transsexual subjects; however, the long‐term physiologic effects …
female to male (FtM) transsexual subjects; however, the long‐term physiologic effects …
Testosterone antagonizes doxorubicin‐induced senescence of cardiomyocytes
P Altieri, C Barisione, E Lazzarini, A Garuti… - Journal of the …, 2016 - Am Heart Assoc
Background Chronic cardiotoxicity is less common in male than in female patients receiving
doxorubicin and other anthracyclines at puberty and adolescence. We hypothesized that …
doxorubicin and other anthracyclines at puberty and adolescence. We hypothesized that …
[HTML][HTML] p38 MAPK and JNK antagonistically control senescence and cytoplasmic p16INK4A expression in doxorubicin-treated endothelial progenitor cells
P Spallarossa, P Altieri, C Barisione, M Passalacqua… - PLoS …, 2010 - journals.plos.org
Patients treated with low-dose anthracyclines often show late onset cardiotoxicity. Recent
studies suggest that this form of cardiotoxicity is the result of a progenitor cell disease. In this …
studies suggest that this form of cardiotoxicity is the result of a progenitor cell disease. In this …