User profiles for P. Thomas

Paul D Thomas

Professor, University of Southern California
Verified email at usc.edu
Cited by 77084

The sequence of the human genome

…, L Chen, M Skupski, G Subramanian, PD Thomas… - science, 2001 - science.org
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

…, H Norppa, DA Eastmond, JD Tucker, P Thomas - …, 2011 - academic.oup.com
Micronuclei (MN) and other nuclear anomalies such as nucleoplasmic bridges (NPBs) and
nuclear buds (NBUDs) are biomarkers of genotoxic events and chromosomal instability. …

Principles of protein folding—a perspective from simple exact models

…, HS Chan, KM Ftebig, DP Yee, PD Thomas - Protein …, 1995 - Wiley Online Library
General principles of protein structure, stability, and folding kinetics have recently been explored
in computer simulations of simple exact lattice models. These models represent protein …

The EAGLE project: simulating the evolution and assembly of galaxies and their environments

…, Y Qu, A Rahmati, T Sawala, PA Thomas… - Monthly Notices of …, 2015 - academic.oup.com
We introduce the Virgo Consortium's Evolution and Assembly of GaLaxies and their
Environments (EAGLE) project, a suite of hydrodynamical simulations that follow the formation of …

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

PS Thomas - Proceedings of the National Academy of …, 1980 - National Acad Sciences
A simple and rapid method for transferring RNA from agarose gels to nitrocellulose paper for
blot hybridization has been developed. Poly(A)+ and ribosomal RNAs transfer efficiently to …

InterPro in 2022

…, I Sillitoe, N Thanki, PD Thomas… - Nucleic acids …, 2023 - academic.oup.com
The InterPro database ( https://www.ebi.ac.uk/interpro/ ) provides an integrative classification
of protein sequences into families, and identifies functionally important domains and …

The InterPro protein families and domains database: 20 years on

…, I Sillitoe, N Thanki, PD Thomas… - Nucleic acids …, 2021 - academic.oup.com
The InterPro database ( https://www.ebi.ac.uk/interpro/ ) provides an integrative classification
of protein sequences into families, and identifies functionally important domains and …

Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective …

…, RJ Francis, C Tang, I Vela, P Thomas… - The Lancet, 2020 - thelancet.com
Background Conventional imaging using CT and bone scan has insufficient sensitivity
when staging men with high-risk localised prostate cancer. We aimed to investigate whether …

Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads+ 5 …

…, K Ramming, HO Douglas Jr, P Thomas… - Cancer, 1981 - Wiley Online Library
One‐hundred‐ninety‐four eligible and evaluable patients with histologically confirmed locally
unresectable adenocarcinoma of the pancreas were randomly assigned to therapy with …

The ENCODE (ENCyclopedia of DNA elements) project

…, ME Portnoy, NF Hansen, PJ Thomas… - Science, 2004 - scholarworks.bwise.kr
The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional elements
in the human genome sequence. The pilot phase of the Project is focused on a specified …