The microencapsulation process in which the removal of the hydrophobic polymer solvent is
achieved by evaporation has been widely reported in recent years for the preparation of …

Although the potential for genomics to contribute to clinical care has long been anticipated,
the pace of defining the risks and benefits of incorporating genomic findings into medical …

The paradigm of individualized drug therapy based on genetics is an ideal that is now
potentially possible. However, translation of pharmacogenomics into practice has encountered …

Importance Guidelines for patients with atherosclerotic cardiovascular disease (ASCVD)
recommend intensive statin therapy and adding nonstatin therapy if low-density lipoprotein …

Background Patients with metastatic urothelial carcinoma have few treatment options after
failure of platinum-based chemotherapy. In this trial, we assessed treatment with atezolizumab…

We report a comprehensive analysis of 412 muscle-invasive bladder cancers characterized
by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the …

… Two-sided 95% CIs and corresponding P values were calculated for all statistical analysis
results. Statistical analyses were performed using SAS version 9.4 (SAS Institute Inc). Efficacy …

We evaluated the safety and efficacy of high-dose, posttransplantation cyclophosphamide (Cy)
to prevent graft rejection and graft-versus-host disease (GVHD) after outpatient …

Somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 occur in gliomas and acute
myeloid leukaemia (AML). Since patients with multiple enchondromas have occasionally …

Background More than half of all patients with advanced urothelial cancer cannot receive
standard, first-line cisplatin-based chemotherapy because of renal dysfunction, poor …