… The significance level chosen for the statistical analysis was P < 0.05. … N-Acetyl-p-benzoquinone
imine (NAPQI), the reactive metabolite of AAP, has previously been shown to induce …

Acute myeloid leukemia (AML) has a high mortality rate despite chemotherapy and transplantation.
Both CXCR4/SDF-1 and VLA-4/VCAM1 axes are involved in leukemia protection but …

The interaction between acute myeloid leukemia cells (AML) with the bone marrow stroma
cells (BMSCs) determines a protective environment that favors tumor development and …

Cyclooxygenase-2 (COX-2) is associated with tumour promotion, inhibition of apoptosis,
angiogenesis and metastasis. Celecoxib, a selective COX-2 inhibitor was investigated, in …

The mild analgesic drug acetaminophen (AAP) induces severe hepatic injury when taken at
excessive doses. Recent evidence shows that the initial form of damage is through apoptosis…

Background Despite a high response rate to chemotherapy, the majority of patients with
acute myeloid leukemia (AML) are destined to relapse due to residual disease in the bone …

Apoptosis plays a critical role in acetaminophen (AAP)‐induced hepatic injury, since
inhibiting apoptosis also prevents the development of acute liver failure. In this study, the …

… Differences were considered significant if a p value of 0.05 or less was obtained. … Likewise,
there was a reduction in the activation of AKT, as shown by diminished p-AKT in response to …

… Absolute NAb positivity and Tab levels were associated with the homologous schedule (with
a beta coefficient of 0.26 with p = 0.027 and a geometric mean ratio 1.41 with p = 0.044, …

Malignant melanoma is a cancer that arises from melanocyte cells in a complex but well-studied
process, and which can only be successfully treated prior to metastasis as it is highly …