Pathogenesis of atherosclerosis in diabetes mellitus
JA Colwell, M Lopes-Virella, PV Halushka - Diabetes care, 1981 - Am Diabetes Assoc
Numerous studies have shown that patients with diabetes mellitus have accelerated atherosclerotic
vascular disease, and major advances in understanding its pathogenesis have been …
vascular disease, and major advances in understanding its pathogenesis have been …
Thromboxane, prostaglandin and leukotriene receptors
PV Halushka, DE Mais, PR Mayeux… - Annual review of …, 1989 - annualreviews.org
… Mais & PV Halushka, unpublished observations]. … Kochel, PI, Halushka, PV 1985. B inding
of a thromboxane All prostaglandin H2 receptor antagonist to washed human platelets. J. …
of a thromboxane All prostaglandin H2 receptor antagonist to washed human platelets. J. …
Opportunities for microRNAs in the crowded field of cardiovascular biomarkers
PV Halushka, AJ Goodwin… - Annual Review of …, 2019 - annualreviews.org
Cardiovascular diseases exist across all developed countries. Biomarkers that can predict
or diagnose diseases early in their pathogeneses can reduce their morbidity and mortality in …
or diagnose diseases early in their pathogeneses can reduce their morbidity and mortality in …
Disposition and metabolism of the flavonoid chrysin in normal volunteers
…, JA Brubaker, UK Walle, PV Halushka - British journal of …, 2001 - Wiley Online Library
Aims To describe the oral disposition of the dietary flavonoid chrysin in healthy volunteers.
Methods Oral 400 mg doses of chrysin were administered to seven subjects. Chrysin and …
Methods Oral 400 mg doses of chrysin were administered to seven subjects. Chrysin and …
Testosterone Increases Human Platelet Thromboxane A2 Receptor Density and Aggregation Responses
AAL Ajayi, R Mathur, PV Halushka - Circulation, 1995 - Am Heart Assoc
Background The incidence of thrombotic cardiovascular disease is greater in men than in
premenopausal women. Testosterone has been implicated as a significant risk factor for …
premenopausal women. Testosterone has been implicated as a significant risk factor for …
Genetic variation in cyclooxygenase 1: effects on response to aspirin
…, LP Walker, PV Halushka - Clinical Pharmacology & …, 2003 - Wiley Online Library
Background A critical clinical application of the Human Genome Project is to identify
functional variation in genes related to disease or responses to xenobiotics. This study moved …
functional variation in genes related to disease or responses to xenobiotics. This study moved …
Mechanism of platelet inhibition by nitric oxide: In vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase
GR Wang, Y Zhu, PV Halushka… - Proceedings of the …, 1998 - National Acad Sciences
Nitric oxide (NO) is a potent vasodilator and inhibitor of platelet activation. NO stimulates
production of cGMP and activates cGMP-dependent protein kinase (G kinase), which by an …
production of cGMP and activates cGMP-dependent protein kinase (G kinase), which by an …
[HTML][HTML] Carbon dioxide is the major metabolite of quercetin in humans
T Walle, UK Walle, PV Halushka - The Journal of nutrition, 2001 - Elsevier
A previous study in ileostomy patients indicated that dietary glucosides of the flavonoid
quercetin are hydrolyzed efficiently in the intestinal lumen, followed by absorption of a large …
quercetin are hydrolyzed efficiently in the intestinal lumen, followed by absorption of a large …
[HTML][HTML] Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury
Y Zhou, P Li, AJ Goodwin, JA Cook, PV Halushka… - Critical Care, 2019 - Springer
Background The acute respiratory distress syndrome (ARDS) is characterized by disruption
of the alveolar-capillary barrier resulting in accumulation of proteinaceous edema and …
of the alveolar-capillary barrier resulting in accumulation of proteinaceous edema and …
[HTML][HTML] Exosomes from endothelial progenitor cells improve the outcome of a murine model of sepsis
Y Zhou, P Li, AJ Goodwin, JA Cook, PV Halushka… - Molecular Therapy, 2018 - cell.com
Microvascular dysfunction leads to multi-organ failure and mortality in sepsis. Our previous
studies demonstrated that administration of exogenous endothelial progenitor cells (EPCs) …
studies demonstrated that administration of exogenous endothelial progenitor cells (EPCs) …