[PDF][PDF] Pharmacokinetic rationale for peritoneal drug administration
RL Dedrick, CE Myers, PM Bungay, VT DeVita - Cancer Treat Rep, 1978 - researchgate.net
Evidence from the peritoneal dialysis literature suggests that the peritoneal permeability of a
number of hydrophilic anticancer drugs may be considerably less than plasma clearance. …
number of hydrophilic anticancer drugs may be considerably less than plasma clearance. …
Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro
PM Bungay, PF Morrison, RL Dedrick - Life sciences, 1990 - Elsevier
… Membrane: For low molecular weight water-soluble solutes the accessible volume fraction
of the membrane, ~Pm, is of the order of the volume fraction occupied by water. Diffusion of …
of the membrane, ~Pm, is of the order of the volume fraction occupied by water. Diffusion of …
The motion of a closely-fitting sphere in a fluid-filled tube
PM Bungay, H Brenner - International Journal of Multiphase Flow, 1973 - Elsevier
Singular perturbation techniques are used to investigate the slow, asymmetric flow around a
sphere positioned eccentrically within a long, circular, cylindrical tube filled with viscous fluid…
sphere positioned eccentrically within a long, circular, cylindrical tube filled with viscous fluid…
AAPS-FDA workshop white paper: microdialysis principles, application and regulatory perspectives
…, E Benfeldt, J Bolinder, R Bullock, PM Bungay… - 2007 - Springer
… The typical total microdialysate volumes of a few μL or less and analyte concentrations in
the pM or nM range present tremendous challenges for the analytical chemist. Thus, it is …
the pM or nM range present tremendous challenges for the analytical chemist. Thus, it is …
Microdialysis of dopamine interpreted with quantitative model incorporating probe implantation trauma
PM Bungay, P Newton‐Vinson, W Isele… - Journal of …, 2003 - Wiley Online Library
Although microdialysis is widely used to sample endogenous and exogenous substances in
vivo, interpretation of the results obtained by this technique remains controversial. The goal …
vivo, interpretation of the results obtained by this technique remains controversial. The goal …
A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide
…, H Kim, S Kim, RJ Lutz, C Galban, PM Bungay… - Experimental eye …, 2006 - Elsevier
Transscleral delivery of triamcinolone acetonide into the vitreous using sub-Tenon's
injections may be a safer alternative to reduce the sight-threatening complications of direct …
injections may be a safer alternative to reduce the sight-threatening complications of direct …
Evaluation of coupled convective–diffusive transport of drugs administered by intravitreal injection and controlled release implant
J Park, PM Bungay, RJ Lutz, JJ Augsburger… - Journal of controlled …, 2005 - Elsevier
A 3-dimensional finite element model was developed to simulate pharmacokinetics in the
eye following drug administration by intravitreal injection and implant for the treatment of …
eye following drug administration by intravitreal injection and implant for the treatment of …
Effects of different semipermeable membranes on in vitro and in vivo performance of microdialysis probes
…, PF Morrison, IN Mefford, PM Bungay - Journal of …, 1990 - Wiley Online Library
… barrels of 500 pm 0.d. 24-gauge TW stainless steel (Small Parts) and inner barrels of 150 pm
0.d… (5 cm long, 1 mm id) packed with 3 pm ODS Hypersil (Shandon) with a mobile phase of …
0.d… (5 cm long, 1 mm id) packed with 3 pm ODS Hypersil (Shandon) with a mobile phase of …
Quantitative assessment of angiogenic responses by the directed in vivo angiogenesis assay
…, ML Miller, JJ Diegmueller, PM Bungay… - The American journal of …, 2003 - Elsevier
One of the major problems in angiogenesis research remains the lack of suitable methods for
quantifying the angiogenic response in vivo. We describe the development and application …
quantifying the angiogenic response in vivo. We describe the development and application …
[HTML][HTML] Analysis of binding at a single spatially localized cluster of binding sites by fluorescence recovery after photobleaching
Cells contain many subcellular structures in which specialized proteins locally cluster.
Binding interactions within such clusters may be analyzed in live cells using models for …
Binding interactions within such clusters may be analyzed in live cells using models for …