Vascular endothelium–gatekeeper of vessel health
PA Cahill, EM Redmond - Atherosclerosis, 2016 - Elsevier
The vascular endothelium is an interface between the blood stream and the vessel wall.
Changes in this single cell layer of the artery wall are believed of primary importance in the …
Changes in this single cell layer of the artery wall are believed of primary importance in the …
Notch and vascular smooth muscle cell phenotype
The Notch signaling pathway is critical for cell fate determination during embryonic development,
including many aspects of vascular development. An emerging paradigm suggests that …
including many aspects of vascular development. An emerging paradigm suggests that …
[HTML][HTML] Nox, reactive oxygen species and regulation of vascular cell fate
…, R Hakimjavadi, EM Redmond, PA Cahill - Antioxidants, 2017 - mdpi.com
The generation of reactive oxygen species (ROS) and an imbalance of antioxidant defence
mechanisms can result in oxidative stress. Several pro-atherogenic stimuli that promote …
mechanisms can result in oxidative stress. Several pro-atherogenic stimuli that promote …
Electron and hole mobility in tris(8‐hydroxyquinolinolato‐N1,O8) aluminum
…, MB Sinclair, VS Valencia, PA Cahill - Applied physics …, 1995 - pubs.aip.org
We have measured the drift mobility of electrons and holes in thin, vapor‐deposited films of
tris(8‐hydroxyquinolinolato‐N1,O8) aluminum using a time of flight photoconductivity …
tris(8‐hydroxyquinolinolato‐N1,O8) aluminum using a time of flight photoconductivity …
Increased MAPK expression and activity in primary human hepatocellular carcinoma
CM Schmidt, IH McKillop, PA Cahill… - … and biophysical research …, 1997 - Elsevier
We investigated the expression and activity of mitogen-activated protein kinase (MAPK) in
human hepatocellular carcinoma (HCC). MAPK expression was determined in five human …
human hepatocellular carcinoma (HCC). MAPK expression was determined in five human …
Physically crosslinked composite hydrogels of PVA with natural macromolecules: structure, mechanical properties, and endothelial cell compatibility
Polyvinyl alcohol (PVA) hydrogels have been considered potentially suitable for applications
as engineered blood vessels because of their structure and mechanical properties. …
as engineered blood vessels because of their structure and mechanical properties. …
C60H2: Synthesis of the Simplest C60 Hydrocarbon Derivative
CC Henderson, PA Cahill - Science, 1993 - science.org
The reaction of C 60 with BH 3 : tetrahydrofuran in toluene followed by hydrolysis yielded C
60 H 2 . This product was separated by high-performance liquid chromatography and …
60 H 2 . This product was separated by high-performance liquid chromatography and …
Thermal behavior and mechanical properties of physically crosslinked PVA/Gelatin hydrogels
… significantly from 3495 Pa for the 1FT hydrogel to 8616 Pa for the 3FT hydrogel ( P < 0.001
). With the coagulation treatment, the G ′ of 1FT significantly increased to 5889 Pa ( P < 0.05 …
). With the coagulation treatment, the G ′ of 1FT significantly increased to 5889 Pa ( P < 0.05 …
Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cells
ME Egan, J Glöckner-Pagel, CA Ambrose, PA Cahill… - Nature medicine, 2002 - nature.com
The most common mutation in cystic fibrosis, ΔF508, results in a cystic fibrosis transmembrane
conductance regulator (CFTR) protein that is retained in the endoplasmic reticulum (ER). …
conductance regulator (CFTR) protein that is retained in the endoplasmic reticulum (ER). …
Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro
Notch signaling has been shown recently to regulate vascular cell fate in adult cells. By
applying a uniform equibiaxial cyclic strain to vascular smooth muscle cells (SMCs), we …
applying a uniform equibiaxial cyclic strain to vascular smooth muscle cells (SMCs), we …