New directions in nicotine vaccine design and use
PR Pentel, MG LeSage - Advances in pharmacology, 2014 - Elsevier
Clinical trials of nicotine vaccines suggest that they can enhance smoking cessation rates
but do not reliably produce the consistently high serum antibody concentrations required. A …
but do not reliably produce the consistently high serum antibody concentrations required. A …
Sex and menstrual cycle differences in the subjective effects from smoked cocaine in humans.
…, S Dudish-Poulsen, D Nelson, PR Pentel… - Experimental and …, 1999 - psycnet.apa.org
To investigate sex and menstrual cycle effects in response to cocaine administration, data
from existing studies were analyzed. First, responses to a single delivery of 0.4 mg/kg smoked …
from existing studies were analyzed. First, responses to a single delivery of 0.4 mg/kg smoked …
Developing the science base for reducing tobacco harm
…, J Jensen, SE Murphy, PR Pentel… - Nicotine & tobacco …, 2007 - academic.oup.com
The University of Minnesota Transdisciplinary Tobacco Use Research Center has been
examining the multiple dimensions and the scientific evidence required to determine the …
examining the multiple dimensions and the scientific evidence required to determine the …
Safety and immunogenicity of a nicotine conjugate vaccine in current smokers
…, A De Vos, G Horwith, PR Pentel - Clinical …, 2005 - Wiley Online Library
Immunotherapy is a novel potential treatment for nicotine addiction. The aim of this study was
to assess the safety and immunogenicity of a nicotine conjugate vaccine, NicVAX, and its …
to assess the safety and immunogenicity of a nicotine conjugate vaccine, NicVAX, and its …
A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats
PR Pentel, DH Malin, S Ennifar, Y Hieda… - Pharmacology …, 2000 - Elsevier
Vaccination of animals to elicit drug-specific antibodies, or the passive transfer of such
antibodies from other animals, can reduce the behavioral effects of drugs such as cocaine and …
antibodies from other animals, can reduce the behavioral effects of drugs such as cocaine and …
[HTML][HTML] Effects of portion size on chronic energy intake
…, CL Dunn, LJ Harnack, AS Levine, PR Pentel… - International Journal of …, 2007 - Springer
Background This study experimentally examined the effects of repeated exposure to different
meal portion sizes on energy intake. Methods Nineteen employees of a county medical …
meal portion sizes on energy intake. Methods Nineteen employees of a county medical …
Physical assessment and differential diagnosis of the poisoned patient
KR Olson, PR Pentel, MT Kelley - Medical Toxicology and Adverse Drug …, 1987 - Springer
The rapid diagnosis and immediate intervention required in patients with serious drug
overdose or poisoning makes toxicological screening of limited value to the emergency …
overdose or poisoning makes toxicological screening of limited value to the emergency …
An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia
…, AM Tucker, PS Portoghese, PR Pentel - … of Pharmacology and …, 2012 - ASPET
Opioid conjugate vaccines have shown promise in attenuating the behavioral effects of heroin
or morphine in animals. The goal of this study was to extend this approach to oxycodone (…
or morphine in animals. The goal of this study was to extend this approach to oxycodone (…
Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats
…, JM Jones, AK Birnbaum, PS Portoghese, PR Pentel - Vaccine, 2012 - Elsevier
Opioid conjugate vaccines have shown promise in animal models as a potential treatment
for opioid addiction. Individual vaccines are quite specific and each targets only a limited …
for opioid addiction. Individual vaccines are quite specific and each targets only a limited …
A fentanyl vaccine alters fentanyl distribution and protects against fentanyl-induced effects in mice and rats
…, TM Harmon, JR Vigliaturo, PR Pentel… - … of Pharmacology and …, 2019 - ASPET
Fentanyl is an extremely potent synthetic opioid that has been increasingly used to
adulterate heroin, cocaine, and counterfeit prescription pills, leading to an increase in opioid-induced …
adulterate heroin, cocaine, and counterfeit prescription pills, leading to an increase in opioid-induced …