Guanyl nucleotides modulate binding to steroid receptors in neuronal membranes.

M Orchinik, TF Murray, PH Franklin… - Proceedings of the …, 1992 - National Acad Sciences
… The resulting pellet was washed in 150 vol of 25 mM Hepes buffer (pH 7.45) and centrifuged
… Assay buffer contained 25 mM Hepes and 10 mM MgCl2 (unless specified otherwise) (pH

Pharmacology of modality-specific transient receptor potential vanilloid-1 antagonists that do not alter body temperature

…, SK Joshi, LG Lewis, M Pai, PH Franklin… - … of Pharmacology and …, 2012 - ASPET
… On the day of the experiment culture medium was removed, and the cells were preincubated
with DPBS, pH 7.4, for 15 min at room temperature. Acidic pH solutions were prepared by …

[PDF][PDF] High affinity [3H] dextrorphan binding in rat brain is localized to a noncompetitive antagonist site of the activated N-methyl-D-aspartate receptor-cation channel.

PH Franklin, TF Murray - Molecular pharmacology, 1992 - researchgate.net
[3HjDextrorphan recognition sites were characterized in rat brain membranes. The
pharmacological profile and regional distribu-tion of [3H] dextrorphan binding sites appear to …

[PDF][PDF] Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility.

G Zhang, PH Franklin, TF Murray - Journal of Pharmacology and …, 1993 - researchgate.net
A1 adenosine receptors in the rat prepinform cortex play an important role in the inhibition
of bicuculline methiodide-induced convulsions. In the present study we evaluated …

Discovery of (R)-1-(7-Chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): A Temperature-Neutral Transient Receptor Potential …

…, P Han, RM Reilly, PH Franklin… - Journal of Medicinal …, 2014 - ACS Publications
… and 37 completely blocked activation of TRPV1 by capsaicin and N-arachidonoyl-dopamine
(NADA, data not shown) (4) but only partially inhibit activation of the channel by protons (pH

Activation of adenosine A1 receptors underlies anticonvulsant effect of CGS21680

G Zhang, PH Franklin, TF Murray - European journal of pharmacology, 1994 - Elsevier
… A total particulate fraction was prepared by homogenizing tissue with a Dounce homogenizer
(A pestle) in 100 volumes of 10 mM Tris buffer (pH 7.7) containing 10 mM EDTA, and …

Nebulization of epinephrine to reduce the severity of brachycephalic obstructive airway syndrome in dogs

PH Franklin, NC Liu, JF Ladlow - Veterinary Surgery, 2021 - Wiley Online Library
… airway syndrome in dogs - Franklin - 2021 - Veterinary Surgery - Wiley Online Library …
Author Contributions: Franklin PH, MA, VetMB, MRCVS: Contributed to the design of the study; …

[PDF][PDF] Adenosine A1 receptor activation mediates suppression of (-) bicuculline methiodide-induced seizures in rat prepiriform cortex.

PH Franklin, G Zhang, ED Tripp… - Journal of Pharmacology …, 1989 - researchgate.net
… of very low doses of 2CIA in this brain area (Franklin et al., 1988). The anticonvulsant action
of 2-… PH: The role of adenosine and its nucleotidea in central synaptic transmission. Pmg. …

Systemic activation of the calcium sensing receptor produces acute effects on vascular tone and circulatory function in uremic and normal rats: focus on central versus …

RM Fryer, JA Segreti, DL Widomski, PH Franklin… - … of Pharmacology and …, 2007 - ASPET
Calcium-sensing receptor (CaR) activation decreases serum parathyroid hormone (PTH)
and Ca 2+ and, despite long-term reductions in mean arterial blood pressure (MAP), may …

Complications and outcomes of cats with coxofemoral luxation treated with hip toggle stabilization using ultrahigh–molecular‐weight‐polyethylene or nylon (2009 …

…, KC Maritato, SC Jones, PH Franklin… - Veterinary …, 2021 - Wiley Online Library
Objective To report overall rate and type of complications and outcomes of cats with coxofemoral
luxation managed with hip toggle stabilization (HTS), to compare rate of postoperative …