… Pit ten ger AL, Amico JA, Fa bian TJ, Kro both FJ, Fo lan MM, Kro both PD: DHEA and re
sponses of pa tients with ad re nal in suf fi ciency to sin gle doses of al pra zo lam. Phar ma co …

Twenty-four healthy adult female volunteers participated in a randomized, three-phase
double-blind crossover trial comparing the single-dose (50 mg) pharmacokinetics of three …

Background Older depressed patients are at high risk for development of hyponatremia after
initiation of the selective serotonin reuptake inhibitor paroxetine, despite clinical monitoring …

The assay methods used to determine the concentrations of the newer benzodiazepines
include electron-capture gas-liquid chromatography, high performace liquid chromatography …

OBJECTIVE: To describe the prevalence of benzodiazepine use, sociodemographic and
physical health factors associated with use, dosages taken, and directions for use among …

The effects of low‐dose estrogen oral contraceptives (OC) on the elimination of the oxidized
benzodiazepines triazolam (TRZ) and alprazolam (ALP) and the conjugated …

Objectives Determination of hepatic and intestinal cytochrome P450 (CYP) 3A activity is
important, because CYP3A substrates show substantial variability in plasma concentrations as a …

Six fasting male subjects (20–32 years of age) received an oral tablet and an IV 1.0-mg dose
of alprazolam in a crossover-design study. Alprazolam plasma concentration in multiple …

Background: Clinical studies of endogenous concentrations of dehydroepiandrosterone (DHEA)
and its sulfated conjugate DHEA-S in depression are limited. This study was designed …

This study was designed to evaluate the relative and absolute bioavailability of triazolam,
0.25 mg, after the administration of the marketed oral tablet and a sublingual prototype wafer; …