Interleukin-1β (IL-1β)-converting enzyme cleaves the IL-1β precursor to mature IL-1β, an
important mediator of inflammation. The identification of the enzyme as a unique cysteine …

Small synthetic molecules termed growth hormone secretagogues (GHSs) act on the
pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone (GH) …

We have previously reported the cloning and characterization of a new orphan G-protein-coupled
receptor (GPC-R), the growth hormone secretagogue receptor (GHS-R), and shown …

Growth hormone release is under tight control by two hypothalamic hormones: growth
hormone-releasing hormone and somatostatin. In addition, synthetic growth hormone …

Motilin is a 22–amino acid peptide hormone expressed throughout the gastrointestinal (GI)
tract of humans and other species. It affects gastric motility by stimulating interdigestive …

GH release is thought to occur under the reciprocal regulation of two hypothalamic peptides,
GH releasing hormone (GHRH) and somatostatin, via their engagement with specific cell …

The recent cloning of a growth hormone secretagogue receptor (GHS-R) from human
pituitary gland and brain identified a third G protein-coupled receptor (GPC-R) involved in the …

By using a combination of genetic, pharmacological, and anatomical approaches, we show
that the melanocortin 4 receptor (MC4R), implicated in the control of food intake and energy …

To assess the contribution of potential central nervous system pathways implicated in the
control of appetite regulation and energy metabolism, it is essential to first identify appropriate …

Objectives : In this study, our goal was to determine if human resistin plays a role in regulating
the uptake of atherogenic low-density lipoproteins in human hepatocytes. Background : …