Heme oxygenase (HO) has antioxidant properties and is up-regulated by reactive oxygen
species (ROS) in ultraviolet-B-irradiated soybean plants. This study shows that nitric oxide (NO…

Platelet activation is a critical process during inflammation, thrombosis, and cancer. Here, we
show that galectin‐1, an endogenous lectin with immunoregulatory properties, plays a key …

Extracellular vesicles (EVs) play key roles in cell biology and may provide new clinical
diagnostics and therapies. However, it has proven difficult to develop protocols for their …

Antioxidant enzymes play a key role in plant tolerance to different types of stress, including
ultraviolet-B (UV-B) radiation. Here we report that nitric oxide (NO) enhances antioxidant …

We were interested in evaluating the ability of the mesenchymal stromal cell (MSC)
population, human umbilical cord perivascular cells (HUCPVCs), to undergo cardiomyocyte …

Human umbilical cord perivascular cells (HUCPVCs) are a readily available source of
mesenchymal stromal cells (MSCs) for cell therapy. We were interested in understanding how …

Perinatal tissues, mainly the placenta and umbilical cord, contain a variety of different somatic
stem and progenitor cell types, including those of the hematopoietic system, multipotent …

Background aims Owing to the lack of biological assays, determining the biological activity
of extracellular vesicles has proven difficult. Here the authors standardized an in vitro assay …

Fabry disease is a lysosomal storage disorder caused by a deficiency of α-galactosidase A (α-gal
A) activity that results in progressive globotriaosylceramide (Gb 3 ) deposition. We …

Background aims Extracellular vesicle (EV) isolation methods are based on different
physicochemical properties and may result in the purification of distinct EV populations. We …