Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
M Tanabe, I Ieiri, N Nagata, K Inoue, S Ito… - … of Pharmacology and …, 2001 - ASPET
To evaluate whether mutations in the human multidrug resistance (MDR)-1 gene correlate
with placental P-glycoprotein (PGP) expression, we sequenced the MDR-1 cDNA and …
with placental P-glycoprotein (PGP) expression, we sequenced the MDR-1 cDNA and …
iPS cells: a game changer for future medicine
H Inoue, N Nagata, H Kurokawa, S Yamanaka - The EMBO journal, 2014 - embopress.org
The induced pluripotent stem cell (i PSC ) technology is instrumental in advancing the fields
of disease modeling and cell transplantation. We herein discuss the various issues …
of disease modeling and cell transplantation. We herein discuss the various issues …
[HTML][HTML] Integrative annotation of 21,037 human genes validated by full-length cDNA clones
…, S Minoshima, K Nagai, H Nagasaki, N Nagata… - PLoS …, 2004 - journals.plos.org
The human genome sequence defines our inherent biological potential; the realization of
the biology encoded therein requires knowledge of the function of each gene. Currently, our …
the biology encoded therein requires knowledge of the function of each gene. Currently, our …
Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma
T Katoh, N Nagata, Y Kuroda, H Itoh… - …, 1996 - academic.oup.com
Genes coding for the glutatione S-transferase M1 (GSTM1) and Theta 1 (GSTT1) proteins
are polymorphic in humans and these genes are absent, or homozygous null, in 10–60% of …
are polymorphic in humans and these genes are absent, or homozygous null, in 10–60% of …
Extraction of gene-disease relations from Medline using domain dictionaries and machine learning
…, Y Tsuruoka, JD Kim, R Shiba, N Nagata… - Biocomputing …, 2006 - World Scientific
We describe a system that extracts disease-gene relations from MedLine. We constructed a
dictionary for disease and gene names from six public databases and extracted relation …
dictionary for disease and gene names from six public databases and extracted relation …
Enhanced coexpression of YB‐1 and DNA topoisomerase II α genes in human colorectal carcinomas
…, Y Nakayama, K Okazaki, N Nagata… - … journal of cancer, 1999 - Wiley Online Library
The transcription factor YB‐1 is expressed in a wide range of cell types and has been implicated
in the regulation of various genes involved in cell proliferation. Nuclear expression of YB…
in the regulation of various genes involved in cell proliferation. Nuclear expression of YB…
[HTML][HTML] High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice
…, H Watarai, E Sekine-Kondo, N Nagata… - The Journal of …, 2010 - Am Soc Clin Investig
Islet transplantation for the treatment of type 1 diabetes mellitus is limited in its clinical
application mainly due to early loss of the transplanted islets, resulting in low transplantation …
application mainly due to early loss of the transplanted islets, resulting in low transplantation …
Genetic polymorphisms of tobacco-and alcohol-related metabolizing enzymes and the risk of hepatocellular carcinoma
…, K Kohshi, T Kawamoto, S Takasawa, N Nagata… - Journal of cancer …, 2003 - Springer
The effect of genetic polymorphisms for glutathione S-transferase ( GST) M1, GSTT1, GSTP1-1
( GSTP1), cytochrome P450 2E1 ( CYP2E1) and aldehyde dehydrogenase 2 ( ALDH2) …
( GSTP1), cytochrome P450 2E1 ( CYP2E1) and aldehyde dehydrogenase 2 ( ALDH2) …
Immunogenicity of induced pluripotent stem cells
K Okita, N Nagata, S Yamanaka - Circulation research, 2011 - Am Heart Assoc
amelioration of the symptoms of rodent disease models after transplantation of iPSC-derived
differentiated cells. For example, hematopoietic stem cells and neuronal precursor cells …
differentiated cells. For example, hematopoietic stem cells and neuronal precursor cells …
Fermentative Production of Poly(β-L-malic acid), a Polyelectrolytic Biopolyester, by Aureobasidium sp
N Nagata, T Nakahara, T Tabuchi - Bioscience, biotechnology, and …, 1993 - Taylor & Francis
Many strains of a black yeast, identified as Aureobasidium sp., were isolated by a selective
medium, which contained mannitol as a main carbon source, and found to produce an …
medium, which contained mannitol as a main carbon source, and found to produce an …