The application of physiologically based pharmacokinetic (PBPK) modeling has developed
rapidly within the pharmaceutical industry and is becoming an integral part of drug discovery …

The simultaneous intake of food and drugs can have a strong impact on drug release,
absorption, distribution, metabolism and/or elimination and consequently, on the efficacy and …

Although oral drug delivery is the preferred administration route and has been used for centuries,
modern drug discovery and development pipelines challenge conventional formulation …

… Analysis of the spatial distribution of registered regional foodstuffs reflects this north-south
divide, with … and opportunities, arising within the two distinct food cultures of ‘north’ and ‘south’. …

Background The major aim of this study was to develop a strategy for predicting human
pharmacokinetics using physiologically based pharmacokinetic (PBPK) modelling. This was …

This article discusses the economic dimensions of agroecological farming systems in
Europe. It firstly theoretically elaborates the reasons why, and under what conditions, …

… N ow that the organic movement is taking off in the industrialised wo rld , g ove rnments ,
international agencies and global agribusiness corporations must stop promoting this …

The release and absorption profile of an oral medication is influenced by the physicochemical
properties of the drug and its formulation, as well as by the anatomy and physiology of the …

Oral administration is the most common route of drug delivery. The absorption of a drug from
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …

Our knowledge of the major mechanisms underlying the effect of food on drug absorption
allows reliable qualitative prediction based on biopharmaceutical properties, which can be …