Matrix Metalloproteinase‐1 is the Major Collagenolytic Enzyme Responsible for Collagen Damage in UV‐irradiated Human Skin

…, H Bhatti, KC Nerusu, N Bhagavathula… - Photochemistry and …, 2003 - Wiley Online Library
Punch biopsies of human skin were obtained 1 day after irradiation with two minimal‐erythema
doses (MED) from either a UVB light source or a Solar Simulator and incubated in organ …

IL-1RL2 and its ligands contribute to the cytokine network in psoriasis

…, K Bailey, D Shows, N Bhagavathula… - The Journal of …, 2010 - journals.aai.org
… Murine IL-1F6 used for injection was an N-terminal truncation mutant beginning at amino …
of IL-1F6 is increased ∼10,000-fold by proteolytic processing near the N terminus (JE Towne, …

A combination of curcumin and ginger extract improves abrasion wound healing in corticosteroid‐impaired hairless rat skin

N Bhagavathula, RL Warner, M DaSilva… - Wound repair and …, 2009 - Wiley Online Library
Hairless rats were topically treated with a combination of 10% curcumin and 3% ginger
extract (or with each agent alone) for a 21‐day period. Following this, the rats were treated …

A Mineral-Rich Extract from the Red Marine Algae Lithothamnion calcareum Preserves Bone Structure and Function in Female Mice on a Western-Style Diet

…, JM Kreider, T Paruchuri, N Bhagavathula… - Calcified tissue …, 2010 - Springer
The purpose of this study was to determine whether a mineral-rich extract derived from the
red marine algae Lithothamnion calcareum could be used as a dietary supplement for …

Matrix metalloproteinases in acute inflammation: induction of MMP-3 and MMP-9 in fibroblasts and epithelial cells following exposure to pro-inflammatory mediators in …

RL Warner, N Bhagavathula, KC Nerusu… - … and molecular pathology, 2004 - Elsevier
… Author links open overlay panel Roscoe L Warner , Narasimharao Bhagavathula , Kamalakar
C … Values shown are means and standard deviations based on n = 3 values in a single …

A mineral-rich red algae extract inhibits polyp formation and inflammation in the gastrointestinal tract of mice on a high-fat diet

…, T Paruchuri, N Bhagavathula… - Integrative cancer …, 2010 - journals.sagepub.com
The purpose of this study was to determine whether a mineral-rich extract derived from the
red marine algae Lithothamnion calcareum could be used as a dietary supplement for …

Fibroblast response to lanthanoid metal ion stimulation: potential contribution to fibrotic tissue injury

…, P Perone, K Walker, N Bhagavathula… - Biological trace element …, 2011 - Springer
The purpose of this study was to compare each of the 14 naturally occurring lanthanoid
metal ions for ability to stimulate pro-fibrotic responses in human dermal fibroblasts. When …

Regulation of E‐cadherin and β‐catenin by Ca2+ in colon carcinoma is dependent on calcium‐sensing receptor expression and function

N Bhagavathula, AW Hanosh… - … journal of cancer, 2007 - Wiley Online Library
An siRNA directed against the extracellular calcium‐sensing receptor (CaSR) was used to
down‐regulate this protein in CBS colon carcinoma cells. In additional studies, we utilized a …

Matrix metalloproteinase-3 (stromelysin-1) in acute inflammatory tissue injury

KC Nerusu, RL Warner, N Bhagavathula… - … and molecular pathology, 2007 - Elsevier
Mice lacking matrix metalloproteinase-3 (MMP-3; stromelysin-1) demonstrated significantly
less injury than their normal counterparts following the formation of IgG-containing immune …

Growth-inhibitory effects of a mineralized extract from the red marine algae, Lithothamnion calcareum, on Ca2+-sensitive and Ca2+-resistant human colon carcinoma …

MN Aslam, N Bhagavathula, T Paruchuri, X Hu… - Cancer Letters, 2009 - Elsevier
Proliferation and differentiation were assessed in a series of human colon carcinoma cell
lines in response to a mineral-rich extract derived from the red marine algae, Lithothamnion …