User profiles for N. K. Patil

Naeem Patil

Vanderbilt University Medical Center
Verified email at vanderbilt.edu
Cited by 1609

The biology of natural killer cells during sepsis

Y Guo, NK Patil, L Luan, JK Bohannon… - …, 2018 - Wiley Online Library
… However, mechanistic understanding of NK cell function during human sepsis is limited. In
… of NK cell biology during sepsis and discuss the challenges associated with modulating NK

Immunobiology of the IL-15/IL-15Rα complex as an antitumor and antiviral agent

Y Guo, L Luan, NK Patil, ER Sherwood - Cytokine & growth factor reviews, 2017 - Elsevier
NK and CD8 + T cells in humanized mice [30]. In particular, RLI promoted proliferation and
differentiation of human NK cell progenitor cells to mature peripheral NK … the reconstituted NK

[HTML][HTML] Targeting immune cell checkpoints during sepsis

NK Patil, Y Guo, L Luan, ER Sherwood - International journal of molecular …, 2017 - mdpi.com
… ex vivo incubation of septic patient’s whole blood with anti-PD-L1 antibody significantly
improved phagocytic function of neutrophils and monocytes, and restored CD8 + T cell and NK

Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria-targeted antioxidant mitigates injury

NK Patil, N Parajuli… - American Journal of …, 2014 - journals.physiology.org
… This work was supported by National Institutes of Health (NIH) Grants R01DK075991 and
RO1GM106419 and NK Patil was supported by a predoctoral fellowship from the American …

Immunotherapy: a promising approach to reverse sepsis-induced immunosuppression

NK Patil, JK Bohannon, ER Sherwood - Pharmacological Research, 2016 - Elsevier
Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
responses to infection (Third International Consensus definition for Sepsis and septic shock). …

Effect of organic manures on plant growth, seed yield and quality of soybean.

HM Maheshbabu, RH Ravi Hunje, NKB Patil… - 2008 - cabidigitallibrary.org
A field experiment was conducted in Dharwad, Karnataka, India, during the kharif season of
2006 to study the effects of organic manures on soyabean (cv. JS-335) growth, seed yield …

[HTML][HTML] TLR agonists as mediators of trained immunity: mechanistic insight and immunotherapeutic potential to combat infection

AM Owen, JB Fults, NK Patil, A Hernandez… - Frontiers in …, 2021 - frontiersin.org
… been studied in monocytes, macrophages, and natural killer (NK) cells which show long-term …
DCs can be activated by TLR signaling or secondary to TLR-activation of NK cells which ‘…

[HTML][HTML] Immune checkpoints: novel therapeutic targets to attenuate sepsis-induced immunosuppression

…, A Hernandez, ER Sherwood, NK Patil - Frontiers in …, 2021 - frontiersin.org
… Increased PD-L1 expression on NK cells within 24 h of ICU … NK cells can augment T
cell proliferation and activation, which involves interactions between 2B4 expressed on NK

[HTML][HTML] The metabolic basis of immune dysfunction following sepsis and trauma

…, JK Bohannon, ER Sherwood, NK Patil - Frontiers in …, 2020 - frontiersin.org
… Various studies have shown the stimulatory effect of serotonin on other immune cells including
Natural Killer cells, dendritic cells, and T cells (120, 121). Studies evaluating the effect of …

[HTML][HTML] MyD88-dependent signaling drives toll-like receptor-induced trained immunity in macrophages

…, TK Patil, J Wang, A Hernandez, NK Patil… - Frontiers in …, 2022 - frontiersin.org
Immunocompromised populations are highly vulnerable to developing life-threatening
infections. Strategies to protect patients with weak immune responses are urgently needed. …