User profiles for N. E. Goeders

Nicholas E Goeders, Ph.D.

Department of Pharmacology, Toxicology & Neuroscience; LSU Health - Shreveport
Verified email at lsuhsc.edu
Cited by 7899

The impact of stress on addiction

NE Goeders - European Neuropsychopharmacology, 2003 - Elsevier
This article will review data obtained from both clinical and preclinical investigations
demonstrating that exposure to stress has a significant impact on drug addiction. The preclinical …

Stress and cocaine addiction

NE Goeders - Journal of Pharmacology and Experimental …, 2002 - ASPET
The hypothalamo-pituitary-adrenal (HPA) axis is involved in all aspects of cocaine self-administration.
Corticosterone seems to be crucial for the acquisition of drug use since self-…

The HPA axis and cocaine reinforcement

NE Goeders - Psychoneuroendocrinology, 2002 - Elsevier
Scientists have been aware of the existence of a complex relationship between stress and
the subsequent activation of the hypothalamic–pituitary–adrenal (HPA) axis and the …

Cortical dopaminergic involvement in cocaine reinforcement

NE Goeders, JE Smith - Science, 1983 - science.org
Neuronal systems involved in the initiation of cocaine reinforcement were investigated by
identifying brain sites where direct application of the drug was reinforcing. This was …

Non-contingent electric footshock facilitates the acquisition of intravenous cocaine self-administration in rats

NE Goeders, GF Guerin - Psychopharmacology, 1994 - Springer
The experiments described below were designed to investigate whether contingent versus
non-contingent electric footshock would affect the acquisition of intravenous cocaine self-…

Methamphetamine use and cardiovascular disease: in search of answers

CG Kevil, NE Goeders, MD Woolard… - … , and vascular biology, 2019 - Am Heart Assoc
While the opioid epidemic has garnered significant attention, the use of methamphetamines
is growing worldwide independent of wealth or region. Following overdose and accidents, …

Self-administration of methionine enkephalin into the nucleus accumbens

NE Goeders, JD Lane, JE Smith - Pharmacology Biochemistry and …, 1984 - Elsevier
Microinfusions of the endogenous opiate neurohumor, methionine enkephalin, into the
nucleus accumbens initiated a reinforcing stimulus in a dose-related manner. The reinforcing …

Stress, motivation, and drug addiction

NE Goeders - Current directions in psychological science, 2004 - journals.sagepub.com
A growing clinical literature indicates that there is a link between substance abuse and stress.
One explanation for the high co-occurrence of stress-related disorders and drug addiction …

Effects of surgical and pharmacological adrenalectomy on the initiation and maintenance of intravenous cocaine self-administration in rats

NE Goeders, GF Guerin - Brain research, 1996 - Elsevier
Previous research has suggested the potential involvement of the hypothalamic-pituitary-adrenal
(HPA) axis in psychostimulant reinforcement. In particular, we have found significant …

A neuroendocrine role in cocaine reinforcement

NE Goeders - Psychoneuroendocrinology, 1997 - Elsevier
Cocaine stimulates the secretion of corticosterone and ACTH, probably through a CRF-related
mechanism, indicating that the drug activates the HPA axis. Indeed, cocaine has been …