User profiles for N Lapierre

Nathan LaPierre

Postdoctoral Scholar, Department of Human Genetics, University of Chicago
Verified email at uchicago.edu
Cited by 600

[HTML][HTML] Impact of the COVID-19 pandemic on older adults: rapid review

…, J Lettre, E Raymond, EL Bussières, N Lapierre… - JMIR aging, 2021 - aging.jmir.org
… A total of 13,452 records remained after duplicates (n=5601) were removed. Upon title
and abstract screening, the number of papers reduced to 630, after the exclusion of 12,822 …

The state of knowledge on technologies and their use for fall detection: A scoping review

N Lapierre, N Neubauer, A Miguel-Cruz… - International journal of …, 2018 - Elsevier
… falls were implemented using data mining techniques (n = 18; 15.25%), support vector
machines (n = 23; 19.49%) and algorithms based on fuzzy logic methods (n = 3; 2.54%). For the …

[HTML][HTML] Critical assessment of metagenome interpretation: the second round of challenges

…, M Kolmogorov, A Korobeynikov, J Kwan, N LaPierre… - Nature …, 2022 - nature.com
… Boxes in boxplots indicate the interquartile range of n results, the center line the median
and arrows the average. Whiskers extend to 1.5 × interquartile range or to the maximum and …

MetaPheno: a critical evaluation of deep learning and machine learning in metagenome-based disease prediction

N LaPierre, CJT Ju, G Zhou, W Wang - Methods, 2019 - Elsevier
The human microbiome plays a number of critical roles, impacting almost every aspect of
human health and well-being. Conditions in the microbiome have been linked to a number of …

[HTML][HTML] Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples

…, M Hochman, SW Simpkins, I Lin, N LaPierre… - Nature Biomedical …, 2021 - nature.com
… Microbiology Laboratory comprising n = 94 SARS-CoV-2-positive samples and n = 286 …
samples collected into either normal saline (n = 128) or TE (n = 170). We showed 96.0% overall …

[HTML][HTML] Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing

…, M Hochman, SW Simpkins, I Lin, N LaPierre… - MedRxiv, 2020 - ncbi.nlm.nih.gov
… (n=128) or TE (n=170). We showed 96.0% overall agreement, 92.0% positive percent
agreement and 97.6% negative percent agreement for all samples and a high correlation (r 2 =0.68…

The relationship between convergence insufficiency and school achievement

JE LÉTOURNEAU, N Lapierre… - Optometry and Vision …, 1979 - journals.lww.com
… We compared the results in one school between students who manifested the signs of
convergence insufficiency (N = 25) and those who did not (N = 251). There were no significant …

[HTML][HTML] Metalign: efficient alignment-based metagenomic profiling via containment min hash

N LaPierre, M Alser, E Eskin, D Koslicki, S Mangul - Genome biology, 2020 - Springer
Metagenomic profiling, predicting the presence and relative abundances of microbes in a
sample, is a critical first step in microbiome analysis. Alignment-based approaches are often …

[HTML][HTML] Identifying causal variants by fine mapping across multiple studies

N LaPierre, K Taraszka, H Huang, R He… - PLoS …, 2021 - journals.plos.org
… In the GWAS, let there be N individuals, all of whom have been … n, we measure a quantitative
trait y n , resulting in the N × 1 column vector Y of phenotypic values. We denote G as the N

[PDF][PDF] Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in a panel of inbred and recombinant inbred mice

AH Khan, JR Bagley, N LaPierre, C Gonzalez-Figueroa… - Cell reports, 2023 - cell.com
To identify addiction genes, we evaluate intravenous self-administration of cocaine or saline
in 84 inbred and recombinant inbred mouse strains over 10 days. We integrate the behavior …