Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

…, HM Sarau, JK Chambers, RN Willette, NV Aiyar… - Nature, 1999 - nature.com
Urotensin-II (U-II) is a vasoactive ‘somatostatin-like’ cyclic peptide which was originally
isolated from fish spinal cords 1 , 2 , and which has recently been cloned from man 3 . Here we …

Three-dimensional shape searching: state-of-the-art review and future trends

N Iyer, S Jayanti, K Lou, Y Kalyanaraman… - Computer-Aided …, 2005 - Elsevier
… ( y i − y ) 2 where x and y are the means of the two vectors and N is the number of
observations or features in each vector. The value of C(x,y) ranges between −1 and +1. …

[HTML][HTML] AG protein-coupled receptor for UDP-glucose

…, P Murdock, L McMillan, J Trill, A Swift, N Aiyar… - Journal of Biological …, 2000 - ASBMB
Uridine 5′-diphosphoglucose (UDP-glucose) has a well established biochemical role as a
glycosyl donor in the enzymatic biosynthesis of carbohydrates. It is less well known that UDP…

Safety recommendations for evaluation and surgery of the head and neck during the COVID-19 pandemic

…, SB Chinn, D Clayburgh, NG Iyer… - … –head & neck …, 2020 - jamanetwork.com
Importance The rapidly expanding novel coronavirus disease 2019 (COVID-19) pandemic,
caused by severe acute respiratory syndrome coronavirus 2, has challenged the medical …

p300/CBP and cancer

NG Iyer, H Özdag, C Caldas - Oncogene, 2004 - nature.com
… Western blots of whole-cell lysates (using p300 N-terminal antibody) and mutational analyses
of limited regions were performed in selected samples. However, these analyses failed to …

The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects

…, P Green, U Shabon, W Bao, N Aiyar… - British journal of …, 2007 - Wiley Online Library
Background and purpose: Atypical cannabinoids are thought to cause vasodilatation
through an as‐yet unidentified ‘CBx’ receptor. Recent reports suggest GPR55 is an atypical …

[HTML][HTML] A cDNA Encoding the Calcitonin Gene-related Peptide Type 1 Receptor (∗)

N Aiyar, K Rand, NA Elshourbagy, Z Zeng… - Journal of Biological …, 1996 - ASBMB
Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse biological effects
including potent vasodilator activity. We report here the cloning of a complementary DNA (cDNA…

Differential vasoconstrictor activity of human urotensin‐II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey

…, HM Sarau, RS Ames, NV Aiyar… - British journal of …, 2000 - Wiley Online Library
Urotensin‐II (U‐II) and its G‐protein‐coupled receptor, GPR14, are expressed within
mammalian cardiac and peripheral vascular tissue and, as such, may regulate mammalian …

Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal brain ischemic damage.

…, RN Willette, AC Sulpizio, NV Aiyar… - Proceedings of the …, 1995 - National Acad Sciences
Focal brain ischemia is the most common event leading to stroke in humans. To understand
the molecular mechanisms associated with brain ischemia, we applied the technique of …

Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells

N Aiyar, J Disa, Z Ao, H Ju, S Nerurkar… - Molecular and cellular …, 2007 - Springer
Lysophosphatidylcholine (LPC) is the major bioactive lipid component of oxidized LDL, thought
to be responsible for many of the inflammatory effects of oxidized LDL described in both …