Cocaine receptors on dopamine transporters are related to self-administration of cocaine

MC Ritz, RJ Lamb, SR Goldberg, MJ Kuhar - Science, 1987 - science.org
Although cocaine binds to several sites in the brain, the biochemical receptor mechanism or
mechanisms associated with its dependence producing properties are unknown. It is shown …

Neurotransmitter transporters: recent progress

SG Amara, MJ Kuhar - Annual review of neuroscience, 1993 - annualreviews.org
It has been known for many years that neurons and glia can accumulate neurotransmitters
by a sodium dependent cotransport process that is, in many respects, similar to systems …

Positron Emission Tomography Reveals Elevated D2 Dopamine Receptors in Drug-Naive Schizophrenics

…, JA Williams, LA O'Tuama, SH Snyder, MJ Kuhar… - Science, 1986 - science.org
In postmortem studies of patients with schizophrenia, D 2 dopamine receptors in the basal
ganglia have been observed to be more numerous than in patients with no history of …

[HTML][HTML] Leptin activates hypothalamic CART neurons projecting to the spinal cord

…, C Aschkenasi, RS Ahima, PR Couceyro, MJ Kuhar… - Neuron, 1998 - cell.com
The adipocyte-derived hormone leptin decreases body weight in part by activating the
sympathetic nervous system, resulting in increased thermogenesis and energy expenditure. We …

Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain

…, JD Petronis, MF Folstein, JKT Toung, MJ Kuhar - Science, 1984 - science.org
D2 dopamine and S2 serotonin receptors were imaged and measured in healthy human
subjects by positron emission tomography after intravenous injection of 11 C-labeled 3-N-…

Imaging dopamine receptors in the human brain by positron tomography

…, SB Rosenbloom, SE Lukas, AV Kramer, MJ Kuhar - Science, 1983 - science.org
Neurotransmitter receptors may be involved in a number of neuropsychiatric disease states.
The ligand 3-N-[ 11 C]methylspiperone, which preferentially binds to dopamine receptors in …

Opiate receptor: autoradiographic localization in rat brain.

CB Pert, MJ Kuhar, SH Snyder - Proceedings of the …, 1976 - National Acad Sciences
Opiate receptor sites in rat brain can be labeled in vivo by [3H]diprenorphine, a potent opiate
antagoinst. Using techniques to minimize diffusion in fresh, frozen, unfixed brain, we have …

Regional distribution of opiate receptor binding in monkey and human brain.

MJ Kuhar, CB Pert, SH Snyder - Nature, 1973 - psycnet.apa.org
Evaluated the localization of opiate receptors in the CNS of 5 rhesus monkeys and 2 male
humans, the latter 10-14 hrs after death. Results of analyses of 3H-dihydromorphine binding …

Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla

SF Atweh, MJ Kuhar - Brain research, 1977 - Elsevier
The localization of opiate receptors in the spinal cord and lower medulla has been elucidated
by the autoradiographic identification of stereospecific [ 3 H]diprenorphine (a potent opiate …

Distribution of α2 agonist binding sites in the rat and human central nervous system: analysis of some functional, anatomic correlates of the pharmacologic effects of …

JR Unnerstall, TA Kopajtic, MJ Kuhar - Brain Research Reviews, 1984 - Elsevier
Using [ 3 H]para-aminoclonidine, α 2 adrenergic binding sites have been mapped in the rat
and human CNS using in vitro labeling autoradiographic techniques. In both the rat and …