User profiles for Mauro Piantelli

Mauro Piantelli

CeSI-Met Foundation, Chieti-Pescara University, Italy
Verified email at unich.it
Cited by 9590

Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential

…, M Brunetti, FB Aiello, M Piantelli - … journal of Cancer, 2000 - Wiley Online Library
Flavonoids are a class of polyphenolic compounds widely distributed in the plant kingdom,
which display a variety of biological activities, including chemoprevention and tumor growth …

Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target

…, G Bonanno, G Ferrandina, M Piantelli… - Cancer chemotherapy …, 1994 - Springer
This study demonstrates that the flavonoid quercetin (Q), a plant-derived compound with low
toxicity in vivo, greatly potentiates the growth-inhibitory activity of Adriamycin (ADR) on MCF-…

Upregulation of Trop-2 quantitatively stimulates human cancer growth

…, R Lattanzio, R De Lange, UH Weidle, M Piantelli… - Oncogene, 2013 - nature.com
Trop-2 is a calcium signal transducer that is associated with transformed cell growth in
experimental systems. However, its role in human cancer remains essentially unknown. In this …

Quercetin inhibits p21‐RAS expression in human colon cancer cell lines and in primary colorectal tumors

…, A Fattorossi, A Capelli, M Piantelli - … journal of cancer, 2000 - Wiley Online Library
Immunocytochemical studies have revealed that 10 μM quercetin reduced the steady state
levels of p21‐ras proteins in both colon cancer cell lines and primary colorectal tumors. …

[HTML][HTML] Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice

…, E Silvestri, R Lattanzio, R La Sorda, M Piantelli… - PloS one, 2011 - journals.plos.org
Background The pathogenic road map leading to Alzheimer's disease (AD) is still not
completely understood; however, a large body of studies in the last few years supports the idea …

90K (Mac-2 BP) and galectins in tumor progression and metastasis

…, P Innominato, M D'egidio, C Natoli, M Piantelli… - Glycoconjugate …, 2002 - Springer
Galectins and their ligands have been implicated in cell transformation and cancer
metastasis, and found to have prognostic value. Mac-2 BP, also known as 90K, is a highly …

Growth‐inhibitory effect of quercetin and presence of type‐II estrogen‐binding sites in human colon‐cancer cell lines and primary colorectal tumors

…, S Mancuso, C Rumi, M Piantelli - … Journal of Cancer, 1992 - Wiley Online Library
We studied the effect of quercetin (Q) on the proliferation of HT‐29, WiDr, COLO 201, and LS‐174T
human colon cancer cell lines. Q, between 10 nM and 10 μM, exerted a dose‐…

[HTML][HTML] Trop-2 is a determinant of breast cancer survival

…, R Lattanzio, P Querzoli, M Pedriali, M Piantelli… - PloS one, 2014 - journals.plos.org
Trop-2 is a calcium signal transducer that drives tumor growth. Anti-Trop-2 antibodies with
selective reactivity versus Trop-2 maturation stages allowed to identify two different pools of …

Phospholipase Cγ1 is required for metastasis development and progression

…, M Mazzoletti, C Rossi, M Iezzi, R Lattanzio, M Piantelli… - Cancer research, 2008 - AACR
Cell motility and invasion play an essential role in the development of metastasis. Evidence
suggests that the enzyme phospholipase Cγ1 (PLCγ1) may be involved in tumor …

Inhibitory effect of quercetin on OVCA 433 cells and presence of type II oestrogen binding sites in primary ovarian tumours and cultured cells

G Scambia, FO Ranelletti, PB Panici, M Piantelli… - British journal of …, 1990 - nature.com
We investigated the effect of the flavonoid quercetin (Q) on the proliferation of the ovarian
cancer cell line OVCA 433. Growth experiments demonstrated that Q exerted a reversible dose-…