Acute painful autoimmune neuropathy: a variant of Guillain‐Barré syndrome

N Yuki, AC Chan, AHY Wong, T Inoue, M Yokai… - Muscle & …, 2018 - Wiley Online Library
Introduction We present a painful small‐fiber neuropathy variant of Guillain‐Barré syndrome
characterized by antecedent infectious symptoms, hyporeflexia, and albuminocytologic …

In silico screening identified novel small-molecule antagonists of PAC1 receptor

I Takasaki, A Watanabe, M Yokai, Y Watanabe… - … of Pharmacology and …, 2018 - ASPET
Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors are present in
the spinal dorsal horn and dorsal root ganglia, suggesting an important role of PACAP …

Spinal astrocytic activation contributes to both induction and maintenance of pituitary adenylate cyclase-activating polypeptide type 1 receptor-induced long-lasting …

M Yokai, T Kurihara, A Miyata - Molecular pain, 2016 - journals.sagepub.com
Background Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors
are present in the spinal dorsal horn and dorsal root ganglia, suggesting an important role of …

[HTML][HTML] Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal …

T Ohnou, M Yokai, T Kurihara… - Journal of …, 2016 - Elsevier
Intrathecal (it) administration of pituitary adenylate cyclase-activating polypeptide (PACAP)
induces long-lasting nociceptive behaviors for more than 60 min in mice, while the …

Spinal astrocyte-neuron lactate shuttle contributes to the PACAP/PAC1 receptor-induced nociceptive behaviors

Y Kambe, M Yokai, I Takasaki, T Kurihara, A Miyata - bioRxiv, 2018 - biorxiv.org
Previously, we showed that spinal pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1
receptor signaling triggers long-lasting pain behaviors through astroglial activation. …

[PDF][PDF] Revised Version

T Onou, M Yokai, T Kurihara, M Hasegawa-Moriyama… - 2016 - researchgate.net
Intrathecal (it) administration of pituitary adenylate cyclase-activating polypeptide (PACAP)
23 induces long-lasting nociceptive behaviors for more than 60 min in mice, while the 24 …

PACAP-induced pain responses are mediated by spinal Cyr61-chemokine signaling pathway

T Ogata, T Maeda, M Yokai, A Miyata… - … for Annual Meeting of …, 2018 - jstage.jst.go.jp
Neuropathic pain such as post-herpetic neuralgia and trigeminal neuralgia is a chronic pain
characterized by severe spontaneous pain and allodynia, however, the mechanisms of the …

Chronic changes in pituitary adenylate cyclase-activating polypeptide and related receptors in response to repeated chemical dural stimulation in rats

X Han, Y Ran, M Su, Y Liu, W Tang, Z Dong… - Molecular …, 2017 - journals.sagepub.com
Background Preclinical experimental studies revealed an acute alteration of pituitary adenylate
cyclase-activating polypeptide in response to a single activation of the trigeminovascular …

[CITATION][C] Spinal astrocytic activation triggered by PACAP-PAC1 signaling pathway contributes to both induction and maintenance of long-term mechanical allodynia

M Yokai, T Kurihara, A Miyata - JOURNAL OF …, 2016 - … SOC EDITORIAL OFF, KANTOHYA …

[CITATION][C] Spinal PACAP-specific receptor activation induces long-lasting mechanical allodynia through the activation of astrocytes

M Yokai, T Kurihara, Y Kambe… - JOURNAL OF …, 2015 - … SOC EDITORIAL OFF, KANTOHYA …