c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity

V Arora, DC Knapp, BL Smith, ML Statdfield… - … of Pharmacology and …, 2000 - ASPET
Expression of c-myc protein is associated with cell proliferation. The present study uses
antisense oligomers to inhibit c-mycexpression in the regenerating rat liver after 70% partial …

Ability of the Vector Tick Boophilus microplus To Acquire and Transmit Babesia equi following Feeding on Chronically Infected Horses with Low-Level Parasitemia

…, GH Palmer, LS Kappmeyer, M Statdfield… - Journal of Clinical …, 2005 - Am Soc Microbiol
The protozoan parasite Babesia equi replicates within erythrocytes. During the acute phase
of infection, B. equi can reach high levels of parasitemia, resulting in a hemolytic crisis. …

[HTML][HTML] Strategies to inhibit Myc and their clinical applicability

JR Whitfield, ME Beaulieu, L Soucek - Frontiers in cell and …, 2017 - frontiersin.org
Myc is an oncogene deregulated in most—perhaps all—human cancers. Each Myc family
member, c-, L-, and N-Myc, has been connected to tumor progression and maintenance. Myc …

[HTML][HTML] Genetic characterization of Theileria equi infecting horses in North America: evidence for a limited source of US introductions

CM Hall, JD Busch, GA Scoles, KA Palma-Cagle… - Parasites & vectors, 2013 - Springer
Background Theileria equi is a tick-borne apicomplexan hemoparasite that causes equine
piroplasmosis. This parasite has a worldwide distribution but the United States was …

[PDF][PDF] Oregon Department of Fish and Wildlife Commission, I am writing you to express my opposition to a recent petition to consider a prohibition of Beaver trapping …

J Wisniewski - dfw.state.or.us
After researching this argument and Coho Salmon life-history requirements, I acknowledge
that Beaver dams do appear to enhance juvenile Coho Salmon habitat under certain …

Within-Season Changes in Cytauxzoon felis Parasitemia in Bobcats

EA Zieman, T Lawson, CK Nielsen… - Journal of …, 2020 - meridian.allenpress.com
Cytauxzoon felis is a pathogen responsible for cytauxzoonosis, a highly fatal disease in
domestic cats. Although most studies of C. felis have focused on this parasite in domestic cats, …

Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats

V Arora, TL Hannah, PL Iversen, RM Brand - Pharmaceutical research, 2002 - Springer
Purpose. To determine if dermal absorption of an antisense phosphorodiamidate Morpholino
oligomers (PMO) can inhibit target gene expression in the liver in vivo. Method. Antisense …

Antisense inhibition of laminin-8 expression reduces invasion of human gliomas in vitro

NM Khazenzon, AV Ljubimov, AJ Lakhter… - Molecular Cancer …, 2003 - AACR
Using gene array technology, we recently observed for the first time an up-regulation of
laminin α4 chain in human gliomas. The data were validated by semiquantitative reverse …

[BOOK][B] Molecular Basis of Resilience

PL Iversen - 2018 - Springer
I spent over 40 years involved in diverse biological research projects. Each project focused
my attention to explore subjects in greater depth. The diversity exemplified differences in …

Fibroblast growth factor receptor signalling is crucial for liver homeostasis and regeneration

H Steiling, T Wüstefeld, P Bugnon, M Brauchle… - Oncogene, 2003 - nature.com
Several growth factors have been suggested to play a crucial role in liver regeneration, but a
functional proof is still missing. Since fibroblast growth factors are important for the initiation …