Background— Intravitreal neovascular diseases, as in ischemic retinopathies, are a major
cause of blindness. Because inflammatory mechanisms influence vitreal neovascularization …

Lysophosphatidic acid (LPA) is a bioactive molecule involved in inflammation, immunity,
wound healing, and neoplasia. Its pleiotropic actions arise presumably by interaction with their …

We reported upregulation of endothelial nitric oxide synthase (eNOS) by PGE 2 in tissues
and presence of perinuclear PGE 2 receptors (EP). We presently studied mechanisms by …

Sweat‐testing remains a key component of the diagnostic workup for cystic fibrosis. However,
it is technically challenging, especially in young children. This review covers technical …

IL-1 is a major proinflammatory cytokine which interacts with the IL-1 receptor I (IL-1RI)
complex, composed of IL-1RI and IL-1R accessory protein subunits. Currently available …

Ischemic retinopathies, such as retinopathy of prematurity and diabetic retinopathy are
characterized by an initial microvascular degeneration, followed by an abnormal hypoxia-induced …

Ischemic proliferative retinopathy develops in various retinal disorders, including retinal vein
occlusion, diabetic retinopathy and retinopathy of prematurity. Ischemic retinopathy remains …

Background and Purpose— Reduced endothelium-dependent vasorelaxation partly due to
loss of nitric oxide (NO) bioavailability occurs in most cases of chronic hypertension. …

Prostanoids exert significant effects on circulatory beds. They play a role in the response of
the vasculature to adjustments in perfusion pressure and oxygen and carbon dioxide tension, …

Microvascular degeneration is an important event in oxygen-induced retinopathy (OIR), a
model of retinopathy of prematurity. Because oxidant stress abundantly generates …