The Wnt/β-catenin signalling pathway appears to operate to maintain the undifferentiated
state of preadipocytes by inhibiting adipogenic gene expression. To define the mechanisms …

OBJECTIVE Carbohydrate-responsive element–binding protein (ChREBP) is a key transcription
factor that mediates the effects of glucose on glycolytic and lipogenic genes in the liver. …

β‐catenin signaling can be both a physiological and oncogenic pathway in the liver. It controls
compartmentalized gene expression, allowing the liver to ensure its essential metabolic …

BACKGROUND & AIMS: The adiponutrin/PNPLA3 (patatin-like phospholipase domain-containing
protein 3) variant I148M has recently emerged as an important marker of human fatty …

Background & Aims In non-alcoholic fatty liver disease (NAFLD), hepatocytes can undergo
necroptosis: a regulated form of necrotic cell death mediated by the receptor-interacting …

Tumor necrosis factor-α (TNFα) is involved in the physiological and biological abnormalities
found in two opposite metabolic situations: cachexia and obesity. In an attempt to identify …

Aims Oleuropein has been recognized as an important medicinal compound because of its
various biological properties, including anti-cancer, antidiabetic and anti-atherosclerotic …

In this study, we show that expression of FoxC2 blocks the capacity of 3T3-L1 preadipocytes
to undergo adipogenesis in the presence of dexamethasone, isobutylmethylxanthine, and …

Adiponutrin is a newly identified nonsecreted adipocyte protein regulated by changes in
energy balance in rodents. We documented the influence of energy balance modification on …

Polycystic ovary syndrome (PCOS) is characterized by an oligo-anovulation, hyperandrogenism
and polycystic ovarian morphology combined with major metabolic disturbances. …