User profiles for Mariarosaria Bucci
Mariarosaria BucciDepartment of Pharmacy University of Naples Federico II Verified email at unina.it Cited by 10345 |
Expression of Concern: Carrageenan‐induced mouse paw oedema is biphasic, age‐weight dependent and displays differential nitric oxide cyclooxygenase‐2 …
Injection of carrageenan 1% (50 μl) in the mouse paw causes a biphasic response: an early
inflammatory response that lasts 6 h and a second late response that peaks at 72 h, …
inflammatory response that lasts 6 h and a second late response that peaks at 72 h, …
In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation
Caveolin-1, the primary coat protein of caveolae, has been implicated as a regulator of
signal transduction through binding of its “scaffolding domain” to key signaling molecules. …
signal transduction through binding of its “scaffolding domain” to key signaling molecules. …
Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a mainstay in the treatment of
inflammatory disease and are among the most widely used drugs worldwide. They are anti-…
inflammatory disease and are among the most widely used drugs worldwide. They are anti-…
Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity
Objective—Recent studies have demonstrated that hydrogen sulfide (H 2 S) is produced within
the vessel wall from l-cysteine regulating several aspects of vascular homeostasis. H 2 S …
the vessel wall from l-cysteine regulating several aspects of vascular homeostasis. H 2 S …
Angiopoietin-2 causes inflammation in vivo by promoting vascular leakage
Angiopoietins (Angs) are endothelium-selective ligands that exert most of their actions
through the Tie-2 receptor. It is widely accepted that Ang-1 promotes the structural integrity of …
through the Tie-2 receptor. It is widely accepted that Ang-1 promotes the structural integrity of …
Biosynthesis of H2S is impaired in non‐obese diabetic (NOD) mice
…, V Vellecco, L De Gruttola, M Bucci… - British journal of …, 2008 - Wiley Online Library
Background and purpose: Hydrogen sulphide (H 2 S) has been involved in cardiovascular
homoeostasis but data about its role in animal models of diabetic pathology are still lacking. …
homoeostasis but data about its role in animal models of diabetic pathology are still lacking. …
Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo
The role of endothelium-derived nitric oxide (NO) in acute inflammation is not known. Here,
we examine acute inflammation in congenic endothelial NO synthase-deficient (eNOS -/- ) …
we examine acute inflammation in congenic endothelial NO synthase-deficient (eNOS -/- ) …
Halipeptins A and B: Two Novel Potent Anti-inflammatory Cyclic Depsipeptides from the Vanuatu Marine Sponge Haliclona species
…, G Bifulco, C Giannini, M Bucci… - Journal of the …, 2001 - ACS Publications
Two new metabolites, named halipeptins A and B, have been isolated from the marine
sponge Haliclona sp. Their structures were determined by extensive use of one- and two-…
sponge Haliclona sp. Their structures were determined by extensive use of one- and two-…
[HTML][HTML] cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation
A growing body of evidence suggests that hydrogen sulfide (H 2 S) is a signaling molecule
in mammalian cells. In the cardiovascular system, H 2 S enhances vasodilation and …
in mammalian cells. In the cardiovascular system, H 2 S enhances vasodilation and …
Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression
…, A Papapetropoulos, M Bucci… - Pigment cell & …, 2015 - Wiley Online Library
In humans, two main metabolic enzymes synthesize hydrogen sulfide (H 2 S): cystathionine
γ lyase ( CSE ) and cystathionine β synthase ( CBS ). A third enzyme, 3‐mercaptopyruvate …
γ lyase ( CSE ) and cystathionine β synthase ( CBS ). A third enzyme, 3‐mercaptopyruvate …