User profiles for Mariarosaria Bucci

Mariarosaria Bucci

Department of Pharmacy University of Naples Federico II
Verified email at unina.it
Cited by 10345

Expression of Concern: Carrageenan‐induced mouse paw oedema is biphasic, age‐weight dependent and displays differential nitric oxide cyclooxygenase‐2 …

I Posadas, M Bucci, F Roviezzo, A Rossi… - British journal of …, 2004 - Wiley Online Library
Injection of carrageenan 1% (50 μl) in the mouse paw causes a biphasic response: an early
inflammatory response that lasts 6 h and a second late response that peaks at 72 h, …

In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation

M Bucci, JP Gratton, RD Rudic, L Acevedo… - Nature medicine, 2000 - nature.com
Caveolin-1, the primary coat protein of caveolae, has been implicated as a regulator of
signal transduction through binding of its “scaffolding domain” to key signaling molecules. …

Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?

S Fiorucci, R Meli, M Bucci, G Cirino - Biochemical pharmacology, 2001 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a mainstay in the treatment of
inflammatory disease and are among the most widely used drugs worldwide. They are anti-…

Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity

M Bucci, A Papapetropoulos, V Vellecco… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—Recent studies have demonstrated that hydrogen sulfide (H 2 S) is produced within
the vessel wall from l-cysteine regulating several aspects of vascular homeostasis. H 2 S …

Angiopoietin-2 causes inflammation in vivo by promoting vascular leakage

F Roviezzo, S Tsigkos, A Kotanidou, M Bucci… - … of Pharmacology and …, 2005 - ASPET
Angiopoietins (Angs) are endothelium-selective ligands that exert most of their actions
through the Tie-2 receptor. It is widely accepted that Ang-1 promotes the structural integrity of …

Biosynthesis of H2S is impaired in non‐obese diabetic (NOD) mice

…, V Vellecco, L De Gruttola, M Bucci… - British journal of …, 2008 - Wiley Online Library
Background and purpose: Hydrogen sulphide (H 2 S) has been involved in cardiovascular
homoeostasis but data about its role in animal models of diabetic pathology are still lacking. …

Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo

M Bucci, F Roviezzo, I Posadas, J Yu… - Proceedings of the …, 2005 - National Acad Sciences
The role of endothelium-derived nitric oxide (NO) in acute inflammation is not known. Here,
we examine acute inflammation in congenic endothelial NO synthase-deficient (eNOS -/- ) …

Halipeptins A and B:  Two Novel Potent Anti-inflammatory Cyclic Depsipeptides from the Vanuatu Marine Sponge Haliclona species

…, G Bifulco, C Giannini, M Bucci… - Journal of the …, 2001 - ACS Publications
Two new metabolites, named halipeptins A and B, have been isolated from the marine
sponge Haliclona sp. Their structures were determined by extensive use of one- and two-…

[HTML][HTML] cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation

M Bucci, A Papapetropoulos, V Vellecco, Z Zhou… - PloS one, 2012 - journals.plos.org
A growing body of evidence suggests that hydrogen sulfide (H 2 S) is a signaling molecule
in mammalian cells. In the cardiovascular system, H 2 S enhances vasodilation and …

Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression

…, A Papapetropoulos, M Bucci… - Pigment cell & …, 2015 - Wiley Online Library
In humans, two main metabolic enzymes synthesize hydrogen sulfide (H 2 S): cystathionine
γ lyase ( CSE ) and cystathionine β synthase ( CBS ). A third enzyme, 3‐mercaptopyruvate …