SH2 domains recognize specific phosphopeptide sequences

…, BG Neel, RB Birge, JE Fajardo, MM Chou… - Cell, 1993 - cell.com
The discovery that Src homology 2 (SH2) domains provide phosphorylation-dependent and
sequence-specific contacts for assembly of receptor signaling complexes has provided a …

[PDF][PDF] Regulation of protein kinase C ζ by PI 3-kinase and PDK-1

MM Chou, W Hou, J Johnson, LK Graham, MH Lee… - Current Biology, 1998 - cell.com
Background: Protein kinase C ζ (PKCζ) is a member of the PKC family of enzymes and is
involved in a wide range of physiological processes including mitogenesis, protein synthesis, …

[HTML][HTML] Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation: a role for the TSC2 tumor suppressor gene in pulmonary …

…, D Noonan, DJ Kwiatkowski, MM Chou… - Journal of Biological …, 2002 - ASBMB
Although the cellular functions ofTSC2 and its protein product, tuberin, are not known, somatic
mutations in the TSC2 tumor suppressor gene are associated with tumor development in …

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

M Nikolic, MM Chou, W Lu, BJ Mayer, LH Tsai - Nature, 1998 - nature.com
Cyclin-dependent kinase 5 (Cdk5) and its neuron-specific regulator p35 ( 1 – 4 ) are essential
for neuronal migration and for the laminar configuration of the cerebral cortex 5 , 6 , 7 . In …

[HTML][HTML] Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion

MR Erickson-Johnson, MM Chou, BR Evers… - Laboratory …, 2011 - Elsevier
Nodular fasciitis (NF) is a relatively common mass-forming and self-limited subcutaneous
pseudosarcomatous myofibroblastic proliferation of unknown pathogenesis. Due to its rapid …

[HTML][HTML] The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1

MM Chou, J Blenis - Cell, 1996 - cell.com
The 70 kDa ribosomal S6 kinase (pp70 S6k ) plays an important role in the progression of
cells through G1 phase of the cell cycle. However, little is known of the signaling molecules …

[PDF][PDF] A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit

…, S Kadauke, E Wang, AW Lau, J Zuber, MM Chou… - Molecular cell, 2009 - cell.com
Mixed lineage leukemia (MLL) and its metazoan Trithorax orthologs have been linked with
the epigenetic maintenance of transcriptional activity. To identify mechanisms by which MLL …

USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis

AM Oliveira, MM Chou - Human pathology, 2014 - Elsevier
USP6 (also known as TRE17) is a ubiquitin-specific protease that was identified as an
oncogene in transfection experiments with Ewing sarcoma DNA 2 decades ago. Until recently, …

TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-κB

…, D Lev, A Welman, GA Blobel, AM Oliveira, MM Chou - Oncogene, 2010 - nature.com
Aneurysmal bone cyst (ABC) is an aggressive, pediatric bone tumor characterized by
extensive destruction of the surrounding bone. Although first described over 60 years ago, its …

Vaginal versus ultrasound examination of fetal occiput position during the second stage of labor

MR Chou, D Kreiser, MM Taslimi, ML Druzin… - American journal of …, 2004 - Elsevier
OBJECTIVE: The purpose of this study was to determine whether ultrasonography is more
accurate than vaginal examination in the determination of fetal occiput position in the second …