SH2 domains recognize specific phosphopeptide sequences
…, BG Neel, RB Birge, JE Fajardo, MM Chou… - Cell, 1993 - cell.com
The discovery that Src homology 2 (SH2) domains provide phosphorylation-dependent and
sequence-specific contacts for assembly of receptor signaling complexes has provided a …
sequence-specific contacts for assembly of receptor signaling complexes has provided a …
[PDF][PDF] Regulation of protein kinase C ζ by PI 3-kinase and PDK-1
MM Chou, W Hou, J Johnson, LK Graham, MH Lee… - Current Biology, 1998 - cell.com
Background: Protein kinase C ζ (PKCζ) is a member of the PKC family of enzymes and is
involved in a wide range of physiological processes including mitogenesis, protein synthesis, …
involved in a wide range of physiological processes including mitogenesis, protein synthesis, …
[HTML][HTML] Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation: a role for the TSC2 tumor suppressor gene in pulmonary …
…, D Noonan, DJ Kwiatkowski, MM Chou… - Journal of Biological …, 2002 - ASBMB
Although the cellular functions ofTSC2 and its protein product, tuberin, are not known, somatic
mutations in the TSC2 tumor suppressor gene are associated with tumor development in …
mutations in the TSC2 tumor suppressor gene are associated with tumor development in …
The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity
M Nikolic, MM Chou, W Lu, BJ Mayer, LH Tsai - Nature, 1998 - nature.com
Cyclin-dependent kinase 5 (Cdk5) and its neuron-specific regulator p35 ( 1 – 4 ) are essential
for neuronal migration and for the laminar configuration of the cerebral cortex 5 , 6 , 7 . In …
for neuronal migration and for the laminar configuration of the cerebral cortex 5 , 6 , 7 . In …
[HTML][HTML] Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion
MR Erickson-Johnson, MM Chou, BR Evers… - Laboratory …, 2011 - Elsevier
Nodular fasciitis (NF) is a relatively common mass-forming and self-limited subcutaneous
pseudosarcomatous myofibroblastic proliferation of unknown pathogenesis. Due to its rapid …
pseudosarcomatous myofibroblastic proliferation of unknown pathogenesis. Due to its rapid …
[HTML][HTML] The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1
MM Chou, J Blenis - Cell, 1996 - cell.com
The 70 kDa ribosomal S6 kinase (pp70 S6k ) plays an important role in the progression of
cells through G1 phase of the cell cycle. However, little is known of the signaling molecules …
cells through G1 phase of the cell cycle. However, little is known of the signaling molecules …
[PDF][PDF] A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit
Mixed lineage leukemia (MLL) and its metazoan Trithorax orthologs have been linked with
the epigenetic maintenance of transcriptional activity. To identify mechanisms by which MLL …
the epigenetic maintenance of transcriptional activity. To identify mechanisms by which MLL …
USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis
AM Oliveira, MM Chou - Human pathology, 2014 - Elsevier
USP6 (also known as TRE17) is a ubiquitin-specific protease that was identified as an
oncogene in transfection experiments with Ewing sarcoma DNA 2 decades ago. Until recently, …
oncogene in transfection experiments with Ewing sarcoma DNA 2 decades ago. Until recently, …
TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-κB
…, D Lev, A Welman, GA Blobel, AM Oliveira, MM Chou - Oncogene, 2010 - nature.com
Aneurysmal bone cyst (ABC) is an aggressive, pediatric bone tumor characterized by
extensive destruction of the surrounding bone. Although first described over 60 years ago, its …
extensive destruction of the surrounding bone. Although first described over 60 years ago, its …
Vaginal versus ultrasound examination of fetal occiput position during the second stage of labor
MR Chou, D Kreiser, MM Taslimi, ML Druzin… - American journal of …, 2004 - Elsevier
OBJECTIVE: The purpose of this study was to determine whether ultrasonography is more
accurate than vaginal examination in the determination of fetal occiput position in the second …
accurate than vaginal examination in the determination of fetal occiput position in the second …