A correlation exists between the ability of tumor cells to aggregate platelets and their
tendency to metastasize. Tumor cell-induced platelet aggregation (TCIPA) facilitates the …

Background: Matrix metalloproteinases (MMPs) digest extracellular matrix components and
might be important mediators of tissue remodeling. Proteinase activated receptor-2 (PAR-2) …

Carnocyclin A (CclA) is a potent antimicrobial peptide from Carnobacterium maltaromaticum
UAL307 that displays a broad spectrum of activity against numerous Gram-positive …

Background: The eosinophil is a prominent cell in allergic lung inflammation and is exposed
to a range of cytokines, including TNF-α, at the site of allergen challenge. Matrix …

Asthma affects an estimated 300 million people worldwide and accounts for 1 of 250 deaths
and 15 million disability-adjusted life years lost annually. Plastic-adherent bone marrow–…

The protein tyrosine kinase Syk is critically involved in immunoreceptor signaling in
hematopoietic cells. Recent studies demonstrate Syk expression in nonhematopoietic cells, …

Bacterial resistance to conventional antibiotics is a major challenge in controlling infectious
diseases and has necessitated the development of novel approaches in antimicrobial …

Escherichia coli export the protein YebF into the extracellular medium by a two-step process.
However, as no general outer membrane protein secretion system common to all E. coli …

Changes in the level of membrane cholesterol regulate a variety of signaling processes
including those mediated by acylated signaling molecules that localize to lipid rafts. Recently …

… Paul Jurasz, 1 Michael W Stewart, 3 Anna Radomski, 1 Fadi Khadour, 1 Marek Duszyk, 2
and Marek W Radomski 1, * … JURASZ P., SAWICKI G., DUSZYK M., SAWICKA J …