Although yohimbine (YOH) has been available for the treatment of male erectile dysfunction
(ED) for longer than Viagra ® , there is a perception that little is known about the clinical …

Background We examined whether a fixed dose of both isosorbide dinitrate and hydralazine
provides additional benefit in blacks with advanced heart failure, a subgroup previously …

Purpose: The goal of this double-blind, placebo-controlled, three-way crossover,
randomized clinical trial was to compare the efficacy and safety of the combination of 6g of L-arginine …

This study examined the effects of the nitric oxide-precursor L-arginine combined with the α
2 -blocker yohimbine on subjective and physiological sexual arousal in postmenopausal …

Objectives : We sought to evaluate the effect of the aldosterone synthase promoter polymorphism
on heart failure outcomes for subjects in the African American Heart Failure Trial (A-…

Background— We previously reported that the fixed-dose combination of isosorbide dinitrate
and hydralazine hydrochloride (FDC I/H) significantly decreased the risk of all-cause death …

Background— Corin, a transmembrane serine protease expressed in cardiomyocytes,
cleaves pro–atrial natriuretic peptide and pro–brain natriuretic peptide (BNP) into biologically …

BACKGROUND: Genetic heterogeneity at the endothelial nitric oxide synthase (NOS3) locus
influences heart failure outcomes. The prevalence of NOS3 variants differs in black and …

… Patients must have prior HF-related events and left ventricular ejection fraction (LVEF) ≤35%
or LVEF <45% with left ventricular internal diastolic dimension >2.9 cm/m 2 . …

… Garay RP, Moura AM, Osborne-Pellegrin MJ, Papadimitriou A, Worcel M. Identification of …
Moura AM, Worcel M. Arterial smooth muscle effects of aldosterone: action on ionic fluxes. …