Because all three components of lower urinary tract control (parasympathetic, sympathetic
and somatic) are intimately associated with serotonin (5-hydroxytryptamine [5HT])- and …

Previous studies showed that the dual serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine
(NE) reuptake inhibitor, duloxetine, increases bladder capacity and urethral sphincter …

In the present study, the role of 5-HT 1A receptors in control of lower urinary tract function in
cats was examined using 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and 5-…

The excitatory neurotransmitter glutamate has been implicated in both migraine and persistent
pain. The identification of the kainate receptor GLU K5 in dorsal root ganglia, the dorsal …

The purpose of this study was to determine feasibility of a novel therapeutic approach to
drug-induced voiding after spinal cord injury (SCI) using a well-characterized, peptide, …

… Bladder and rectal pressures were amplified using a bridge amplifier (Transbridge 4 M,
World Precision Instruments). At the end of the experiment, rats were euthanized with an …

Calcium-activated potassium channels are attractive targets for the development of
therapeutics for overactive bladder. In the current study, we addressed the role of calcium-activated …

Amino diacid 3, a highly selective competitive GluR5 kainate receptor antagonist, exhibited
high GluR5 receptor affinity and selectivity over other glutamate receptors. Its diethyl ester …

Purpose : The purpose of the present study was to determine the peripheral neural pathways,
spinal distribution, sizes, and peptide transmitter content of primary afferent and autonomic …

One cannot survive without regularly urinating and defecating. People with neurological
injury (spinal cord injury, traumatic brain injury, stroke) or disease (multiple sclerosis, …