A review of natural products and plants as potential antidiabetic drugs
MD Ivorra, M Paya, A Villar - Journal of ethnopharmacology, 1989 - Elsevier
The present paper reviews the active, natural principles and crude extracts of plants which
have been experimentally studied for hypoglycemic activity in the last ten years. …
have been experimentally studied for hypoglycemic activity in the last ten years. …
Antihyperglycemic and insulin-releasing effects of beta-sitosterol 3-beta-D-glucoside and its aglycone, beta-sitosterol.
MD Ivorra, MP D'ocon, M Paya… - Archives internationales de …, 1988 - europepmc.org
The effect of beta-sitosterol 3-beta-glucoside (antihyperglycemic principle isolated from the
aerial part of Centaurea seridis L. var. maritima Lge.) and its aglycone on plasma insulin and …
aerial part of Centaurea seridis L. var. maritima Lge.) and its aglycone on plasma insulin and …
Hypoglycemic and insulin release effects of tormentic acid: a new hypoglycemic natural product
MD Ivorra, M Paya, A Villar - Planta Medica, 1988 - thieme-connect.com
The effect of tormentic acid, a natural product isolated from Poterium ancistroides, was studied
in normoglycemic, hyperglycemic, and streptozotocin diabetic rats. This principle lowered …
in normoglycemic, hyperglycemic, and streptozotocin diabetic rats. This principle lowered …
Different β‐adrenoceptor subtypes coupling to cAMP or NO/cGMP pathways: implications in the relaxant response of rat conductance and resistance vessels
…, P D'Ocon, E Vila, MD Ivorra - British journal of …, 2013 - Wiley Online Library
Background and Purpose To analyse the relative contribution of β 1 ‐, β 2 ‐ and β 3 ‐adrenoceptors
(Adrb) to vasodilatation in conductance and resistance vessels, assessing the role …
(Adrb) to vasodilatation in conductance and resistance vessels, assessing the role …
[HTML][HTML] Beyond lectures and practical courses: Teaching pharmacology using imaginative pedagogical tools
…, P D'Ocón, MD Ivorra, M Ferrándiz… - Pharmacological …, 2024 - Elsevier
Pharmacology has broadened its scope considerably in recent decades. Initially, it was of
interest to chemists, doctors and pharmacists. In recent years, however, it has been …
interest to chemists, doctors and pharmacists. In recent years, however, it has been …
Different expression of adrenoceptors and GRKs in the human myocardium depends on heart failure ethiology and correlates to clinical variables
…, J Agüero, L Almenar, MD Ivorra… - American Journal …, 2012 - journals.physiology.org
Downregulation of β 1 - adrenergic receptors (β 1 -ARs) and increased expression/function
of G-protein-coupled receptor kinase 2 (GRK2) have been observed in human heart failure, …
of G-protein-coupled receptor kinase 2 (GRK2) have been observed in human heart failure, …
Antihypertensive mechanism of lactoferrin-derived peptides: angiotensin receptor blocking effect
…, C Arce, P Manzanares, MD Ivorra… - Journal of agricultural …, 2014 - ACS Publications
Looking for antihypertensive mechanisms beyond ACE inhibition, we assessed whether
lactoferrin (LF)-derived peptides can act as receptor blockers to inhibit vasoconstriction induced …
lactoferrin (LF)-derived peptides can act as receptor blockers to inhibit vasoconstriction induced …
Correlation between mRNA levels and functional role of α1-adrenoceptor subtypes in arteries: evidence of α1L as a functional isoform of the α1A-adrenoceptor
…, K Ziani, R Gisbert, MD Ivorra… - American Journal …, 2005 - journals.physiology.org
The mRNA levels for the three α 1 -adrenoceptor subtypes, α 1A , α 1B , and α 1D , were
quantified by real-time RT-PCR in arteries from Wistar rats. The α 1D -adrenoceptor was …
quantified by real-time RT-PCR in arteries from Wistar rats. The α 1D -adrenoceptor was …
Effect of beta-sitosterol-3-beta-D-glucoside on insulin secretion in vivo in diabetic rats and in vitro in isolated rat islets of Langerhans.
MD Ivorra, M Paya, A Villar - Die Pharmazie, 1990 - europepmc.org
Beta-Sitosterol-3-beta-D-glucoside (1) has been reported to be the active antidiabetic agent
of Centaurea seridis L. var. maritima. The present study examines the effect of oral …
of Centaurea seridis L. var. maritima. The present study examines the effect of oral …
2, 3, 9-and 2, 3, 11-Trisubstituted tetrahydroprotoberberines as D2 dopaminergic ligands
…, A Galán, E Angelina, RD Enriz, MD Ivorra… - European journal of …, 2013 - Elsevier
Dopamine-mediated neurotransmission plays an important role in relevant psychiatric and
neurological disorders. Nowadays, there is an enormous interest in the development of new …
neurological disorders. Nowadays, there is an enormous interest in the development of new …