Molecular mechanisms of selective estrogen receptor modulator (SERM) action

M Dutertre, CL Smith - Journal of Pharmacology and Experimental …, 2000 - ASPET
In females, estrogens play a key role in reproduction and have beneficial effects on the skeletal,
cardiovascular, and central nervous systems. Most estrogenic responses are mediated …

The clinical phenotype associated with myositis-specific and associated autoantibodies: a meta-analysis revisiting the so-called antisynthetase syndrome

…, Q Reynaud, I Durieu, S Durupt, M Dutertre… - Autoimmunity …, 2014 - Elsevier
Objective To describe the clinical spectrum associated with aminoacyl-transfer RNA synthetase
(ARS) autoantibodies in patients with idiopathic inflammatory myositis defined according …

DNA damage: RNA-binding proteins protect from near and far

M Dutertre, S Lambert, A Carreira… - Trends in biochemical …, 2014 - cell.com
Recent work, including large-scale genetic and molecular analyses, identified RNA-binding
proteins (RBPs) as major players in the prevention of genome instability. These studies …

Zika virus: high infectious viral load in semen, a new sexually transmitted pathogen?

JM Mansuy, M Dutertre, C Mengelle… - The Lancet Infectious …, 2016 - thelancet.com
The recent, rapid spread of Zika virus in South America and increasing reports of cases of
congenital abnormalities spatiotemporally associated with Zika virus infections led WHO to …

FRAP reveals that mobility of oestrogen receptor-α is ligand-and proteasome-dependent

DL Stenoien, K Patel, MG Mancini, M Dutertre… - Nature cell …, 2001 - nature.com
Here we report the use of fluorescence recovery after photobleaching (FRAP) to examine
the intranuclear dynamics of fluorescent oestrogen receptor-α (ER). After bleaching, …

[HTML][HTML] Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage

…, S Roman-Roman, M Dutertre… - Nature …, 2016 - nature.com
Hotspot mutations in the spliceosome gene SF3B1 are reported in ∼20% of uveal melanomas.
SF3B1 is involved in 3′-splice site (3′ss) recognition during RNA splicing; however, …

Hormonal and cellular regulation of Sertoli cell anti-Müllerian hormone production in the postnatal mouse.

L Al-Attar, K Noël, M Dutertre, C Belville… - The Journal of …, 1997 - Am Soc Clin Investig
… Testes embedded in paraffin wax were serially sectioned at 5 m and mounted on slides
coated with 3-aminopropyl triethoxy-silane (Sigma Chemical Co., St. Quentin Fallavier, France). …

[HTML][HTML] RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation

…, S Samaan, FO Desmet, LC Tranchevent, M Dutertre… - Cell reports, 2014 - cell.com
The RNA helicases DDX5 and DDX17 are members of a large family of highly conserved
proteins that are involved in gene-expression regulation; however, their in vivo targets and …

Cotranscriptional exon skipping in the genotoxic stress response

M Dutertre, G Sanchez, MC De Cian, J Barbier… - Nature structural & …, 2010 - nature.com
Pre-mRNA splicing is functionally coupled to transcription, and genotoxic stresses can
enhance alternative exon inclusion by affecting elongating RNA polymerase II. We report here …

Follicle-stimulating hormone increases testicular Anti-Mullerian hormone (AMH) production through sertoli cell proliferation and a nonclassical cyclic adenosine 5 …

…, P Bedecarrás, TR Kumar, M Dutertre… - Molecular …, 2003 - academic.oup.com
Anti-Müllerian hormone (AMH) production by testicular Sertoli cells is high before puberty
and can be further induced by FSH. Our objective was to delineate the mechanisms by which …