Heart tissue possesses complex structural organization on multiple scales, from macro- to
nano-, but nanoscale control of cardiac function has not been extensively analyzed. Inspired …

Three pancreatic beta-cell lines have been established from insulinomas derived from
transgenic mice carrying a hybrid insulin-promoted simian virus 40 tumor antigen gene. The beta …

The transfer of POPs in food of animal origin has been studied by a meta-analysis of 28 peer-reviewed
articles using transfer rate (TR) for milk and eggs and bioconcentration factors (…

We observed previously that estrogen treatment increased the transcript levels of several
mitochondrial DNA (mtDNA)-encoded genes for mitochondrial respiratory chain (MRC) …

Chromosomal instability appears to be key to the pathogenesis of malignant transformation
in human cancers, yet the precise molecular mechanisms underlying chromosomal …

FANCM remodels branched DNA structures and plays essential roles in the cellular
response to DNA replication stress. Here, we show that FANCM forms a conserved DNA-remodeling …

In the yeast Saccharomyces cerevisiae, mitochondria are elongated organelles which form
a reticulum around the cell periphery. To determine the mechanism by which mitochondrial …

Background Antiretroviral therapy (ART) halts HIV-1 replication, decreasing viremia to below
the detection limit of clinical assays. However, some individuals experience persistent …

Introduction Contractile networks are fundamental to many cellular functions, particularly
cytokinesis and cell motility. Contractile networks depend on myosin-II mechanochemistry to …

Fanconi anemia (FA) is a genetically heterogeneous chromosome instability syndrome
associated with congenital abnormalities, bone marrow failure, and cancer predisposition. Eight …