[HTML][HTML] Cytokines induced neutrophil extracellular traps formation: implication for the inflammatory disease condition
Neutrophils (PMNs) and cytokines have a critical role to play in host defense and systemic
inflammatory response syndrome (SIRS). Neutrophil extracellular traps (NETs) have been …
inflammatory response syndrome (SIRS). Neutrophil extracellular traps (NETs) have been …
Reactive oxygen species‐induced activation of ERK and p38 MAPK mediates PMA‐induced NETs release from human neutrophils
RS Keshari, A Verma, MK Barthwal… - Journal of cellular …, 2013 - Wiley Online Library
Neutrophils/polymorphonuclear leukocytes (PMNs), an important component of innate
immune system, release extracellular traps (NETs) to eliminate invaded pathogens; however …
immune system, release extracellular traps (NETs) to eliminate invaded pathogens; however …
Macrophages: an elusive yet emerging therapeutic target of atherosclerosis
… of 5-lipoxygenase-activating protein (FLAP) by MK-886 decreases atherosclerosis in
ApoE/LDLR-double knockout … Inhibition of FLAP by MK-886 showed protection of these animals.…
ApoE/LDLR-double knockout … Inhibition of FLAP by MK-886 showed protection of these animals.…
Nitric oxide donors release extracellular traps from human neutrophils by augmenting free radical generation
High availability of NO, oxidative stress and neutrophil extracellular trap (NETs) contents
are often noticed at the site of inflammation/infection. Studies from this lab and others have …
are often noticed at the site of inflammation/infection. Studies from this lab and others have …
Increased myeloperoxidase enzyme activity in plasma is an indicator of inflammation and onset of sepsis
INTRODUCTION: Circulating lipopolysaccharides released from bacteria may activate both
neutrophils and monocytes. The activated neutrophils release myeloperoxidase (MPO), a …
neutrophils and monocytes. The activated neutrophils release myeloperoxidase (MPO), a …
Oxidized LDL induced extracellular trap formation in human neutrophils via TLR-PKC-IRAK-MAPK and NADPH-oxidase activation
Neutrophil extracellular traps (NETs) formation was initially linked with host defence and
extracellular killing of pathogens. However, recent studies have highlighted their inflammatory …
extracellular killing of pathogens. However, recent studies have highlighted their inflammatory …
Anti-platelet effects of Curcuma oil in experimental models of myocardial ischemia-reperfusion and thrombosis
Extensive research on the mechanism of action and medicinal importance of curcumin
obtained from turmeric (Curcuma longa) has unfolded its potential therapeutic value against …
obtained from turmeric (Curcuma longa) has unfolded its potential therapeutic value against …
Neutrophil extracellular traps contain mitochondrial as well as nuclear DNA and exhibit inflammatory potential
…, BS Srinag, H Krishnamurthy, MK Barthwal… - Cytometry Part …, 2012 - Wiley Online Library
Neutrophils expel extracellular traps (NETs) to entrap and exterminate the invaded micro‐organisms.
Acute/chronic inflammatory disorders are often observed with aberrantly enhanced …
Acute/chronic inflammatory disorders are often observed with aberrantly enhanced …
[HTML][HTML] Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival
MK Barthwal, P Sathyanarayana, CN Kundu… - Journal of Biological …, 2003 - ASBMB
Mixed lineage kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase (MAPKKK)
that activates c-jun N-terminal kinase (JNK) and can induce cell death in neurons. By …
that activates c-jun N-terminal kinase (JNK) and can induce cell death in neurons. By …
[HTML][HTML] Nitric oxide-mediated apoptosis of neutrophils through caspase-8 and caspase-3-dependent mechanism
…, T Chandra, J Kumaravelu, MK Barthwal… - Cell Death & …, 2016 - nature.com
Neutrophils play an indispensable role in killing of invading pathogens by enhancing
reactive oxygen species (ROS) and NO generation, and subsequently undergoing apoptosis. …
reactive oxygen species (ROS) and NO generation, and subsequently undergoing apoptosis. …