Neutrophils (PMNs) and cytokines have a critical role to play in host defense and systemic
inflammatory response syndrome (SIRS). Neutrophil extracellular traps (NETs) have been …

Neutrophils/polymorphonuclear leukocytes (PMNs), an important component of innate
immune system, release extracellular traps (NETs) to eliminate invaded pathogens; however …

… of 5-lipoxygenase-activating protein (FLAP) by MK-886 decreases atherosclerosis in
ApoE/LDLR-double knockout … Inhibition of FLAP by MK-886 showed protection of these animals.…

High availability of NO, oxidative stress and neutrophil extracellular trap (NETs) contents
are often noticed at the site of inflammation/infection. Studies from this lab and others have …

INTRODUCTION: Circulating lipopolysaccharides released from bacteria may activate both
neutrophils and monocytes. The activated neutrophils release myeloperoxidase (MPO), a …

Neutrophil extracellular traps (NETs) formation was initially linked with host defence and
extracellular killing of pathogens. However, recent studies have highlighted their inflammatory …

Extensive research on the mechanism of action and medicinal importance of curcumin
obtained from turmeric (Curcuma longa) has unfolded its potential therapeutic value against …

Neutrophils expel extracellular traps (NETs) to entrap and exterminate the invaded micro‐organisms.
Acute/chronic inflammatory disorders are often observed with aberrantly enhanced …

Mixed lineage kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase (MAPKKK)
that activates c-jun N-terminal kinase (JNK) and can induce cell death in neurons. By …

Neutrophils play an indispensable role in killing of invading pathogens by enhancing
reactive oxygen species (ROS) and NO generation, and subsequently undergoing apoptosis. …