Several series of pyrido[2,3-d]pyrimidine derivatives were synthesized by reaction of aryl-methyleneacetoacetates
with different aminopyrimidines. The solid-state structure of the methyl …

Several bicyclic dihydropyrimidines were synthesized and evaluated for their calcium
antagonistic activities by comparison with the usual 1,4-dihydropyridine calcium antagonist …

The four stereoisomers of methyl tetrahydrofuran-2-ylmethyl 2,6-dimethyl-4-(o-nitrophenyl)-1,4-dihydro-pyridine-3,5-dicarboxilate
(furnidipine), have been synthesized and separated by …

The ability of PCA 4248 [2-(phenylthio)ethyl-5-methoxycarbonyl- 2,4,6-trimethyl-1,4-dihydropyridine-3-carboxylate]
to block PAF-induced systemic hypotension and protein-rich plasma …

PCA 4233 [2-(phenylthio)ethyl-5-ethoxycarbonyl-2,4,6-trimethyl- 1,4-dihydropyridine-3-carboxylate]
and PCA 4248 [2-(phenylthio) ethyl-5-methoxycarbonyl-2, 4, 6-trimethyl-1, 4-…

… Many of the products in development are characterised by the presence of a 2,6-di-tert-butylphenol
moiety, and have been studied as both cyclooxygenase (CO) and 5-LO inhibitors. A variety …

PCA 50941 is a novel 1,4-dihydropyridine derivative. Its vasoconstricting effects prompted a
systematic comparison with the prototypic Ca 2+ channel activator, bay K 8644. The two …

1,5-Bis-(N-benzyl-N,N-diethylammionium)diethyl ether, dichloride (BBDE Cl) has been tested
as phase transfer catalyst. Several test reactions have been performed, comparing yields …

The four stereoisomers of methyl tetrahydrofuran-2-ylmethyl 2,6-dimethyl-4-(o-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxilate
(furnidipine), have been synthesized and separated by …

1,5-Bis-(N-benzyl-N,N-diethylammionium)diethyl ether, dichloride (BBDE Cl) has been tested
as phase transfer catalyst. Several test reactions have been performed, comparing yields …