Control of liver 6-phosphofructokinase by fructose 2, 6-bisphosphate and other effectors.
E Van Schaftingen, MF Jett, L Hue… - Proceedings of the …, 1981 - National Acad Sciences
Rat liver 6-phosphofructokinase (ATP-D-fructose-6-phosphate 1-phosphotransferase, EC
2.7.1.11) was partially purified free of interfering enzymes by a rapid procedure. Fructose 2,6-…
2.7.1.11) was partially purified free of interfering enzymes by a rapid procedure. Fructose 2,6-…
RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists
…, D Srinivasan, APDW Ford, MF Jett - British journal of …, 2006 - Wiley Online Library
Prostacyclin (PGI 2 ) possesses various physiological functions, including modulation of
nociception, inflammation and cardiovascular activity. Elucidation of these functions has been …
nociception, inflammation and cardiovascular activity. Elucidation of these functions has been …
Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat
MF Jett, CS Ramesha, CD Brown, S Chiu… - … of Pharmacology and …, 1999 - ASPET
The marked analgesic efficacy of ketorolac in humans, relative to other nonsteroidal anti-inflammatory
drugs (NSAIDs), has lead to speculation as to whether additional non-NSAID …
drugs (NSAIDs), has lead to speculation as to whether additional non-NSAID …
The effects of mexiletine, desipramine and fluoxetine in rat models involving central sensitization
MF Jett, J McGuirk, D Waligora, JC Hunter - Pain, 1997 - journals.lww.com
… We have shown previously ( Jett and Michelson, 1996 ) that the agitation response corresponds
well with other formalin-induced, pain-related behaviors, such as flinching and licking ( …
well with other formalin-induced, pain-related behaviors, such as flinching and licking ( …
Pharmacological characteristics of Ro 115–1240, a selective α1A/1L‐adrenoceptor partial agonist: a potential therapy for stress urinary incontinence
DR Blue, DV Daniels, JR Gever, MF Jett… - BJU …, 2004 - Wiley Online Library
OBJECTIVE To describe the preclinical pharmacology of Ro 115–1240, a peripherally acting
selective α 1A/1L ‐adrenoceptor (AR) partial agonist, compared with the α 1A/1L ‐AR full …
selective α 1A/1L ‐adrenoceptor (AR) partial agonist, compared with the α 1A/1L ‐AR full …
Discovery and SAR development of 2-(phenylamino) imidazolines as postacyclin receptor antagonists
…, R Salazar, T Chang, D Chang, MF Jett… - Bioorganic & medicinal …, 2004 - Elsevier
On the basis of screening hits (1a, b), a series of selective, high affinity prostacyclin receptor
antagonists was developed. The optimized lead compound 25d [(4, 5-dihydro-1H-imidazol-2 …
antagonists was developed. The optimized lead compound 25d [(4, 5-dihydro-1H-imidazol-2 …
The formalin test in rat: validation of an automated system
MF Jett, S Michelson - Pain, 1996 - journals.lww.com
A novel, computer-driven, dynamic-force detector was validated for use in measuring the
formalin-induced agitation response. Intraplantar administration of formalin (0.25–5%) …
formalin-induced agitation response. Intraplantar administration of formalin (0.25–5%) …
Regulation of glycogen synthase. Phosphorylation specifities of cAMP-dependent and cAMP-independent kinases for skeletal muscle synthase
TR Soderling, MF Jett, NJ Hutson… - Journal of Biological …, 1977 - ohsu.elsevierpure.com
A cAMP-independent synthase kinase has been partially purified from rabbit skeletal
muscle by ion exchange chromatography on DEAE-cellulose and P-cellulose. This kinase …
muscle by ion exchange chromatography on DEAE-cellulose and P-cellulose. This kinase …
Identification of membrane-bound calcium, calmodulin-dependent protein kinase II in canine heart
MF Jett, CM Schworer, M Bass, TR Soderling - Archives of biochemistry …, 1987 - Elsevier
Phospholamban, the putative regulatory proteolipid of the Ca 2 /Mg 2+ ATPase in cardiac
sarcoplasmic reticulum, was selectively phosphorylated by a Ca 2+ /calmodulin (CaM)-…
sarcoplasmic reticulum, was selectively phosphorylated by a Ca 2+ /calmodulin (CaM)-…
Phosphorylation site specificities of glycogen synthase kinases: determination by peptide mapping using high-performance liquid chromatography
H Juhl, VS Sheorain, CM Schworer, MF Jett… - Archives of Biochemistry …, 1983 - Elsevier
A method is described which separates the various phosphorylation sites in glycogen synthase
based on reverse phase high-performance liquid chromatography (HPLC) of tryptic 32 P-…
based on reverse phase high-performance liquid chromatography (HPLC) of tryptic 32 P-…